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Environmental Factors Modulate the Role of orf21 Sigma Factor in Clavulanic Acid Production in Streptomyces Clavuligerus ATCC27064

Sigma factors and sigma factor-related mechanisms control antibiotic production in Streptomyces. In this contribution, the orf21 gene was overexpressed in the wild-type strain of Streptomyces clavuligerus ATCC2764, yielding S. clavuligerus/pIORF21, to further evaluate its regulatory effect on clavul...

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Detalles Bibliográficos
Autores principales:	Patiño, Luisa F., Aguirre-Hoyos, Vanessa, Pinilla, Laura I., Toro, León F., Ríos-Estepa, Rigoberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869649/ https://www.ncbi.nlm.nih.gov/pubmed/35200432 http://dx.doi.org/10.3390/bioengineering9020078

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