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Identification of the Kinase-Substrate Recognition Interface between MYPT1 and Rho-Kinase

Protein kinases exert physiological functions through phosphorylating their specific substrates; however, the mode of kinase–substrate recognition is not fully understood. Rho-kinase is a Ser/Thr protein kinase that regulates cytoskeletal reorganization through phosphorylating myosin light chain (ML...

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Detalles Bibliográficos
Autores principales: Amano, Mutsuki, Kanazawa, Yoko, Kozawa, Kei, Kaibuchi, Kozo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869655/
https://www.ncbi.nlm.nih.gov/pubmed/35204659
http://dx.doi.org/10.3390/biom12020159