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Non-Pharmacological Interventions for Wandering/Aberrant Motor Behaviour in Patients with Dementia

Background: Aberrant motor behaviour or wandering refers to aimless movement without a specific purpose. Wandering is common in patients with dementia and leads to early institutionalization and caregivers’ burden. Non-pharmacological interventions should be also considered as a first-line solution...

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Autores principales: Dimitriou, Tatiana, Papatriantafyllou, John, Konsta, Anastasia, Kazis, Dimitrios, Athanasiadis, Loukas, Ioannidis, Panagiotis, Koutsouraki, Efrosini, Tegos, Thomas, Tsolaki, Magda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869749/
https://www.ncbi.nlm.nih.gov/pubmed/35203894
http://dx.doi.org/10.3390/brainsci12020130
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author Dimitriou, Tatiana
Papatriantafyllou, John
Konsta, Anastasia
Kazis, Dimitrios
Athanasiadis, Loukas
Ioannidis, Panagiotis
Koutsouraki, Efrosini
Tegos, Thomas
Tsolaki, Magda
author_facet Dimitriou, Tatiana
Papatriantafyllou, John
Konsta, Anastasia
Kazis, Dimitrios
Athanasiadis, Loukas
Ioannidis, Panagiotis
Koutsouraki, Efrosini
Tegos, Thomas
Tsolaki, Magda
author_sort Dimitriou, Tatiana
collection PubMed
description Background: Aberrant motor behaviour or wandering refers to aimless movement without a specific purpose. Wandering is common in patients with dementia and leads to early institutionalization and caregivers’ burden. Non-pharmacological interventions should be also considered as a first-line solution for the wandering because current pharmacological treatment has serious side-effects. Methods: A cross-over randomised controlled trial (RCT) with 60 participants of all stages and different types of dementia was conducted in Greece. The sample was randomly assigned in 6 different groups of 10 participants each. Every intervention lasted for 5 days, and there were 2 days as a wash-out period. There was no drop-out rate. The measurements used were the Mini Mental State Examination (MMSE), Addenbrooke’s Cognitive Examination Revised (ACE-R), Geriatric Depression Scale (GDS), Functional Rating Scale for Symptoms in Dementia (FRSSD), and Neuropsychiatric Inventory (NPI). The interventions that were evaluated were reminiscence therapy (RT), music therapy (MT), and physical exercise (PE). Results: NPI scores were reduced in the group receiving PE (p = 0.006). When MT (p = 0.018) follows PE, wandering symptoms are reduced further. RT should follow MT in order to reduce wandering more (p = 0.034). The same combination was effective for the caregivers’ burden as well; PE (p = 0.004), MT (p = 0.036), RT (p = 0.039). Conclusions: An effective combination that can reduce wandering symptoms in all stages and types of dementia was found: The best order was PH-MT-RT. The same combination in the same order reduced caregivers’ burden.
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spelling pubmed-88697492022-02-25 Non-Pharmacological Interventions for Wandering/Aberrant Motor Behaviour in Patients with Dementia Dimitriou, Tatiana Papatriantafyllou, John Konsta, Anastasia Kazis, Dimitrios Athanasiadis, Loukas Ioannidis, Panagiotis Koutsouraki, Efrosini Tegos, Thomas Tsolaki, Magda Brain Sci Article Background: Aberrant motor behaviour or wandering refers to aimless movement without a specific purpose. Wandering is common in patients with dementia and leads to early institutionalization and caregivers’ burden. Non-pharmacological interventions should be also considered as a first-line solution for the wandering because current pharmacological treatment has serious side-effects. Methods: A cross-over randomised controlled trial (RCT) with 60 participants of all stages and different types of dementia was conducted in Greece. The sample was randomly assigned in 6 different groups of 10 participants each. Every intervention lasted for 5 days, and there were 2 days as a wash-out period. There was no drop-out rate. The measurements used were the Mini Mental State Examination (MMSE), Addenbrooke’s Cognitive Examination Revised (ACE-R), Geriatric Depression Scale (GDS), Functional Rating Scale for Symptoms in Dementia (FRSSD), and Neuropsychiatric Inventory (NPI). The interventions that were evaluated were reminiscence therapy (RT), music therapy (MT), and physical exercise (PE). Results: NPI scores were reduced in the group receiving PE (p = 0.006). When MT (p = 0.018) follows PE, wandering symptoms are reduced further. RT should follow MT in order to reduce wandering more (p = 0.034). The same combination was effective for the caregivers’ burden as well; PE (p = 0.004), MT (p = 0.036), RT (p = 0.039). Conclusions: An effective combination that can reduce wandering symptoms in all stages and types of dementia was found: The best order was PH-MT-RT. The same combination in the same order reduced caregivers’ burden. MDPI 2022-01-19 /pmc/articles/PMC8869749/ /pubmed/35203894 http://dx.doi.org/10.3390/brainsci12020130 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Dimitriou, Tatiana
Papatriantafyllou, John
Konsta, Anastasia
Kazis, Dimitrios
Athanasiadis, Loukas
Ioannidis, Panagiotis
Koutsouraki, Efrosini
Tegos, Thomas
Tsolaki, Magda
Non-Pharmacological Interventions for Wandering/Aberrant Motor Behaviour in Patients with Dementia
title Non-Pharmacological Interventions for Wandering/Aberrant Motor Behaviour in Patients with Dementia
title_full Non-Pharmacological Interventions for Wandering/Aberrant Motor Behaviour in Patients with Dementia
title_fullStr Non-Pharmacological Interventions for Wandering/Aberrant Motor Behaviour in Patients with Dementia
title_full_unstemmed Non-Pharmacological Interventions for Wandering/Aberrant Motor Behaviour in Patients with Dementia
title_short Non-Pharmacological Interventions for Wandering/Aberrant Motor Behaviour in Patients with Dementia
title_sort non-pharmacological interventions for wandering/aberrant motor behaviour in patients with dementia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869749/
https://www.ncbi.nlm.nih.gov/pubmed/35203894
http://dx.doi.org/10.3390/brainsci12020130
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