Cargando…

Assays Used for Discovering Small Molecule Inhibitors of YAP Activity in Cancers

SIMPLE SUMMARY: Cancer is a disease in which cells grow in an uncontrolled manner. This can be due to excessive cell proliferation or reduced cell death or a combination of the two. The Hippo signaling pathway, when misregulated, promotes excessive growth and cancer development by inducing uncontrol...

Descripción completa

Detalles Bibliográficos
Autores principales:	Maity, Subhajit, Gridnev, Artem, Misra, Jyoti R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869775/ https://www.ncbi.nlm.nih.gov/pubmed/35205777 http://dx.doi.org/10.3390/cancers14041029

Ejemplares similares

Structure-based discovery of a novel small-molecule inhibitor of TEAD palmitoylation with anticancer activity
por: Gridnev, Artem, et al.
Publicado: (2022)

Emerging Mechanisms of Growth and Patterning Regulation by Dachsous and Fat Protocadherins
por: Gridnev, Artem, et al.
Publicado: (2022)

Photoresponsive Small Molecule Enzyme Mimics
por: Adak, Soumen, et al.
Publicado: (2022)

Methods to Discover and Evaluate Proteasome Small Molecule Stimulators
por: Coleman, Rachel A., et al.
Publicado: (2019)

Discovering small molecules as Wnt inhibitors that promote heart regeneration and injury repair
por: Xie, Shuying, et al.
Publicado: (2019)

Use of mRNA expression signatures to discover small molecule inhibitors of skeletal muscle atrophy
por: Adams, Christopher M., et al.
Publicado: (2015)

Discovering small-molecule therapeutics against SARS-CoV-2
por: Tiwari, Vaibhav, et al.
Publicado: (2020)

Strategy To Discover Diverse Optimal Molecules in the Small Molecule Universe
por: Rupakheti, Chetan, et al.
Publicado: (2015)

Small molecule inhibitors targeting the cancers
por: Liu, Gui‐Hong, et al.
Publicado: (2022)

Terminal Protection of Small Molecule-Linked DNA for Small Molecule–Protein Interaction Assays
por: Hu, Cui, et al.
Publicado: (2014)

Using Pharmacogenomic Databases for Discovering Patient-Target Genes and Small Molecule Candidates to Cancer Therapy
por: Belizário, José E., et al.
Publicado: (2016)

Non-peptidic Cruzain Inhibitors with Trypanocidal Activity Discovered by Virtual Screening and In Vitro Assay
por: Wiggers, Helton J., et al.
Publicado: (2013)

Small molecule tyrosine kinase inhibitors in pancreatic cancer
por: Gupta, Sachin, et al.
Publicado: (2008)

Hepatotoxicity of Small Molecule Protein Kinase Inhibitors for Cancer
por: Viganò, Mauro, et al.
Publicado: (2023)

Small molecules inhibiting the nuclear localization of YAP/TAZ for chemotherapeutics and chemosensitizers against breast cancers
por: Oku, Yusuke, et al.
Publicado: (2015)

Photoresponsive Small Molecule Inhibitors for the Remote Control of Enzyme Activity
por: Laczi, Dóra, et al.
Publicado: (2022)

Novel Nucleic Acid Binding Small Molecules Discovered Using DNA-Encoded Chemistry
por: Litovchick, Alexander, et al.
Publicado: (2019)

Small Molecule Inhibitors of CXCR4
por: Debnath, Bikash, et al.
Publicado: (2013)

Probing Bioactive Chemical Space to Discover RNA-Targeted Small Molecules
por: Wicks, Sarah L., et al.
Publicado: (2023)

Inhibitors Targeting YAP in Gastric Cancer: Current Status and Future Perspectives
por: Yong, Jiaxin, et al.
Publicado: (2021)

Small-Molecule Activators of Insulin-Degrading Enzyme Discovered through High-Throughput Compound Screening
por: Cabrol, Christelle, et al.
Publicado: (2009)

Secondary Resistant Mutations to Small Molecule Inhibitors in Cancer Cells
por: Hamid, Abdulaziz B., et al.
Publicado: (2020)

Small-Molecule Inhibitors and Degraders Targeting KRAS-Driven Cancers
por: Hyun, Soonsil, et al.
Publicado: (2021)

Small-Molecule Inhibitors Targeting FEN1 for Cancer Therapy
por: Yang, Fan, et al.
Publicado: (2022)

Assay development for the discovery of small-molecule inhibitors of YadA adhesion to collagen
por: Saragliadis, Athanasios, et al.
Publicado: (2019)

Small Molecule Inhibitors for Unc-51-like Autophagy-Activating Kinase Targeting Autophagy in Cancer
por: Karmacharya, Ujjwala, et al.
Publicado: (2023)

Small Molecules—Prospective Novel HCMV Inhibitors
por: Bogner, Elke, et al.
Publicado: (2021)

Glycoengineering of Therapeutic Antibodies with Small Molecule Inhibitors
por: Li, Shasha, et al.
Publicado: (2021)

Small Molecule Inhibitors of Influenza Virus Entry
por: Chen, Zhaoyu, et al.
Publicado: (2021)

Discovering monoacylglycerol lipase inhibitors by a combination of fluorogenic substrate assay and activity-based protein profiling
por: Deng, Hui, et al.
Publicado: (2022)

The role of YAP/TAZ activity in cancer metabolic reprogramming
por: Zhang, Xiaodong, et al.
Publicado: (2018)

Small molecule KDM4s inhibitors as anti-cancer agents
por: Lin, Hongzhi, et al.
Publicado: (2018)

Small molecules discovered in a pathway screen target the Rho pathway in cytokinesis
por: Castoreno, Adam B., et al.
Publicado: (2010)

A machine learning and network framework to discover new indications for small molecules
por: Gilvary, Coryandar, et al.
Publicado: (2020)

Discovering Novel Small Molecule Compound for Prevention of Monoclonal Antibody Self-Association †
por: Lui, Lok Hin, et al.
Publicado: (2022)

Small-Molecule Inhibitors (SMIs) as an Effective Therapeutic Strategy for Endometrial Cancer
por: Megino-Luque, Cristina, et al.
Publicado: (2020)

Targeting the Ubiquitin-Proteasome System for Cancer Therapeutics by Small-Molecule Inhibitors
por: LaPlante, Gabriel, et al.
Publicado: (2021)

Identification of Small-Molecule Inhibitors of Brucella Diaminopimelate Decarboxylase by Using a High-Throughput Screening Assay
por: Bie, Pengfei, et al.
Publicado: (2020)

Identification of Small-Molecule Inhibitors of the Salmonella FraB Deglycase Using a Live-Cell Assay
por: Sabag-Daigle, Anice, et al.
Publicado: (2023)

Novel small molecule EGFR inhibitors as candidate drugs in non-small cell lung cancer
por: Berardi, Rossana, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_r7bco1id4kkkpdc0o4kph92k13