The Antianginal Drug Perhexiline Displays Cytotoxicity against Colorectal Cancer Cells In Vitro: A Potential for Drug Repurposing

SIMPLE SUMMARY: Cancer cells frequently have an altered metabolism to support their increased proliferative and invasive activity. Perhexiline, a drug used to treat some cardiovascular diseases, inhibits some of the reported changes in the metabolism of cancer cells. We show that treatment with this...

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Detalles Bibliográficos
Autores principales: Dhakal, Bimala, Li, Celine Man Ying, Li, Runhao, Yeo, Kenny, Wright, Josephine A., Gieniec, Krystyna A., Vrbanac, Laura, Sammour, Tarik, Lawrence, Matthew, Thomas, Michelle, Lewis, Mark, Perry, Joanne, Worthley, Daniel L., Woods, Susan L., Drew, Paul, Sallustio, Benedetta C., Smith, Eric, Horowitz, John D., Maddern, Guy J., Licari, Giovanni, Fenix, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869789/
https://www.ncbi.nlm.nih.gov/pubmed/35205791
http://dx.doi.org/10.3390/cancers14041043

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