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The Cationic Amphiphilic Drug Hexamethylene Amiloride Eradicates Bulk Breast Cancer Cells and Therapy-Resistant Subpopulations with Similar Efficiencies

SIMPLE SUMMARY: A limitation to successful therapeutic outcomes for breast and other cancer patients is the ability of small subsets of tumor cells to resist the apoptotic cell death provoked by currently employed therapeutic agents. These therapy-resistant cancer stem cell populations can then seed...

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Detalles Bibliográficos
Autores principales: Berg, Anastasia L., Rowson-Hodel, Ashley, Hu, Michelle, Keeling, Michael, Wu, Hao, VanderVorst, Kacey, Chen, Jenny J., Hatakeyama, Jason, Jilek, Joseph, Dreyer, Courtney A., Wheeler, Madelyn R., Yu, Ai-Ming, Li, Yuanpei, Carraway, Kermit L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869814/
https://www.ncbi.nlm.nih.gov/pubmed/35205696
http://dx.doi.org/10.3390/cancers14040949

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