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The Cationic Amphiphilic Drug Hexamethylene Amiloride Eradicates Bulk Breast Cancer Cells and Therapy-Resistant Subpopulations with Similar Efficiencies
SIMPLE SUMMARY: A limitation to successful therapeutic outcomes for breast and other cancer patients is the ability of small subsets of tumor cells to resist the apoptotic cell death provoked by currently employed therapeutic agents. These therapy-resistant cancer stem cell populations can then seed...
Autores principales: | Berg, Anastasia L., Rowson-Hodel, Ashley, Hu, Michelle, Keeling, Michael, Wu, Hao, VanderVorst, Kacey, Chen, Jenny J., Hatakeyama, Jason, Jilek, Joseph, Dreyer, Courtney A., Wheeler, Madelyn R., Yu, Ai-Ming, Li, Yuanpei, Carraway, Kermit L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869814/ https://www.ncbi.nlm.nih.gov/pubmed/35205696 http://dx.doi.org/10.3390/cancers14040949 |
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