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Spatial and Genomic Correlates of HIV-1 Integration Site Targeting
HIV-1 integrase and capsid proteins interact with host proteins to direct preintegration complexes to active transcription units within gene-dense regions of chromosomes for viral DNA integration. Analyses of spatially-derived genomic DNA coordinates, such as nuclear speckle-associated domains, lami...
Autores principales: | Singh, Parmit Kumar, Bedwell, Gregory J., Engelman, Alan N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869898/ https://www.ncbi.nlm.nih.gov/pubmed/35203306 http://dx.doi.org/10.3390/cells11040655 |
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