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p53 in Proximal Tubules Mediates Chronic Kidney Problems after Cisplatin Treatment

Nephrotoxicity is a major side-effect of cisplatin in chemotherapy, which can occur acutely or progress into chronic kidney disease (CKD). The protein p53 plays an important role in acute kidney injury induced by cisplatin, but its involvement in CKD following cisplatin exposure is unclear. Here, we...

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Detalles Bibliográficos
Autores principales:	Fu, Shuangshuang, Hu, Xiaoru, Ma, Zhengwei, Wei, Qingqing, Xiang, Xiaohong, Li, Siyao, Wen, Lu, Liang, Yumei, Dong, Zheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870044/ https://www.ncbi.nlm.nih.gov/pubmed/35203361 http://dx.doi.org/10.3390/cells11040712

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