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Synergistic Cytokine Production by ATP and PGE(2) via P2X4 and EP(3) Receptors in Mouse Bone-Marrow-Derived Mast Cells

ATP is an important intercellular messenger in the extracellular space. In mast cells (MCs), ATP stimulates the ionotropic P2X4 receptor (P2X4R), resulting in enhanced degranulation and exacerbation of acute allergic reactions. In this study, we investigate whether ATP regulates inflammatory cytokin...

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Detalles Bibliográficos
Autores principales:	Obayashi, Kosuke, Yoshida, Kazuki, Ito, Masa-aki, Mori, Tetsuya, Yamamoto, Kimiko, Imai, Toshiyashu, Matsuoka, Isao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870111/ https://www.ncbi.nlm.nih.gov/pubmed/35203267 http://dx.doi.org/10.3390/cells11040616

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