Cargando…
A Transcriptional Link between HER2, JAM-A and FOXA1 in Breast Cancer
Overexpression of the human epidermal growth factor receptor-2 (HER2) is associated with aggressive disease in breast and certain other cancers. At a cellular level, the adhesion protein Junctional Adhesion Molecule-A (JAM-A) has been reported to regulate the expression of HER3 via a transcriptional...
Autores principales: | Cruz, Rodrigo G. B., Madden, Stephen F., Brennan, Kieran, Hopkins, Ann M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870165/ https://www.ncbi.nlm.nih.gov/pubmed/35203384 http://dx.doi.org/10.3390/cells11040735 |
Ejemplares similares
-
Functional Antagonism of Junctional Adhesion Molecule-A (JAM-A), Overexpressed in Breast Ductal Carcinoma In Situ (DCIS), Reduces HER2-Positive Tumor Progression
por: Smith, Yvonne E., et al.
Publicado: (2022) -
Human Epidermal Growth Factor Receptor-3 Expression Is Regulated at Transcriptional Level in Breast Cancer Settings by Junctional Adhesion Molecule-A via a Pathway Involving Beta-Catenin and FOXA1
por: Cruz, Rodrigo G. B., et al.
Publicado: (2021) -
A functional link between FOXA1 and breast cancer SNPs
por: Katika, Madhumohan R, et al.
Publicado: (2013) -
Functions of novel Junctional Adhesion Molecule-A (JAM-A) inhibitor in breast cancer cells
por: Lim, XY, et al.
Publicado: (2015) -
Assessing the effect of mutant JAM-A overexpression on downstream signalling in breast cancer cells
por: Chu, JSM, et al.
Publicado: (2015)