Cargando…
Prevalence of Sleep Disorders, Risk Factors and Sleep Treatment Needs of Adolescents and Young Adult Childhood Cancer Patients in Follow-Up after Treatment
SIMPLE SUMMARY: Sleep disorders negatively impact adolescent and young adult childhood cancer patients’ physical and psychosocial health. Early recognition might improve timely treatment. This national cohort study describes subjective sleep disorders (using a validated self-report questionnaire acc...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870170/ https://www.ncbi.nlm.nih.gov/pubmed/35205674 http://dx.doi.org/10.3390/cancers14040926 |
_version_ | 1784656673967702016 |
---|---|
author | Peersmann, Shosha H. M. Grootenhuis, Martha A. van Straten, Annemieke Kerkhof, Gerard A. Tissing, Wim J. E. Abbink, Floor de Vries, Andrica C. H. Loonen, Jacqueline Kremer, Leontien C. M. Kaspers, Gertjan J. L. van Litsenburg, Raphaële R. L. |
author_facet | Peersmann, Shosha H. M. Grootenhuis, Martha A. van Straten, Annemieke Kerkhof, Gerard A. Tissing, Wim J. E. Abbink, Floor de Vries, Andrica C. H. Loonen, Jacqueline Kremer, Leontien C. M. Kaspers, Gertjan J. L. van Litsenburg, Raphaële R. L. |
author_sort | Peersmann, Shosha H. M. |
collection | PubMed |
description | SIMPLE SUMMARY: Sleep disorders negatively impact adolescent and young adult childhood cancer patients’ physical and psychosocial health. Early recognition might improve timely treatment. This national cohort study describes subjective sleep disorders (using a validated self-report questionnaire according to international diagnostic criteria) in childhood cancer patients after treatment, including all types of diagnoses. Sleep disorder prevalence rates ranged from 1.8–9.6%. Insomnia and circadian rhythm sleep disorders were most commonly reported and more prevalent than in the general population. Female sex, young adulthood (18–26 years old) and co-morbid health conditions were risk factors for having a sleep disorder, but cancer-related factors were not. The most commonly used sleep medication was melatonin, which exceeded use described in the general population. Patients with a sleep disorder expressed an unmet need for sleep treatment. Screening for sleep disorders after cancer might improve access to treatment and support childhood cancer patients to maintain optimal health and quality of life. ABSTRACT: Background: Sleep disorders negatively impact adolescent and young adult childhood cancer patients’ physical and psychosocial health. Early recognition improves timely treatment. We therefore studied the prevalence of subjective sleep disorders, risk factors and sleep treatment needs after completion of childhood cancer treatment. Methods: Childhood cancer patients (12–26 years old), ≥6 months after treatment, were invited to fill out the Holland Sleep Disorders Questionnaire, which distinguishes six sleep disorders in substantial agreement with the International Classification of Sleep Disorders, second edition (ICSD-2). They additionally indicated sleep treatment needs. Prevalence rates and needs were displayed in percentages. Logistic regression models were used for risk factors. Results: 576 patients participated (response rate 55.8%)—49.5% females, mean age 17.0 years, 44.4% hemato-oncology, 31.9% solid tumors, 23.6% neuro-oncology. Prevalence rates were: insomnia (9.6%), circadian rhythm sleep disorder (CRSD; 8.1%), restless legs syndrome (7.6%), parasomnia (3.5%), hypersomnia (3.5%) and sleep-related breathing disorders (1.8%). Female sex, comorbid health conditions and young adulthood seem to be risk factors for sleep disorders, but cancer-related factors were not. Differing per sleep disorder, 42–72% wanted help, but only 0–5.6% received sleep treatment. Conclusions: Insomnia and CRSD were most prevalent. An unmet need for sleep treatment was reported by childhood cancer patients during follow-up. Screening for sleep disorders after cancer might improve access to treatment and patient wellbeing. |
format | Online Article Text |
id | pubmed-8870170 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-88701702022-02-25 Prevalence of Sleep Disorders, Risk Factors and Sleep Treatment Needs of Adolescents and Young Adult Childhood Cancer Patients in Follow-Up after Treatment Peersmann, Shosha H. M. Grootenhuis, Martha A. van Straten, Annemieke Kerkhof, Gerard A. Tissing, Wim J. E. Abbink, Floor de Vries, Andrica C. H. Loonen, Jacqueline Kremer, Leontien C. M. Kaspers, Gertjan J. L. van Litsenburg, Raphaële R. L. Cancers (Basel) Article SIMPLE SUMMARY: Sleep disorders negatively impact adolescent and young adult childhood cancer patients’ physical and psychosocial health. Early recognition might improve timely treatment. This national cohort study describes subjective sleep disorders (using a validated self-report questionnaire according to international diagnostic criteria) in childhood cancer patients after treatment, including all types of diagnoses. Sleep disorder prevalence rates ranged from 1.8–9.6%. Insomnia and circadian rhythm sleep disorders were most commonly reported and more prevalent than in the general population. Female sex, young adulthood (18–26 years old) and co-morbid health conditions were risk factors for having a sleep disorder, but cancer-related factors were not. The most commonly used sleep medication was melatonin, which exceeded use described in the general population. Patients with a sleep disorder expressed an unmet need for sleep treatment. Screening for sleep disorders after cancer might improve access to treatment and support childhood cancer patients to maintain optimal health and quality of life. ABSTRACT: Background: Sleep disorders negatively impact adolescent and young adult childhood cancer patients’ physical and psychosocial health. Early recognition improves timely treatment. We therefore studied the prevalence of subjective sleep disorders, risk factors and sleep treatment needs after completion of childhood cancer treatment. Methods: Childhood cancer patients (12–26 years old), ≥6 months after treatment, were invited to fill out the Holland Sleep Disorders Questionnaire, which distinguishes six sleep disorders in substantial agreement with the International Classification of Sleep Disorders, second edition (ICSD-2). They additionally indicated sleep treatment needs. Prevalence rates and needs were displayed in percentages. Logistic regression models were used for risk factors. Results: 576 patients participated (response rate 55.8%)—49.5% females, mean age 17.0 years, 44.4% hemato-oncology, 31.9% solid tumors, 23.6% neuro-oncology. Prevalence rates were: insomnia (9.6%), circadian rhythm sleep disorder (CRSD; 8.1%), restless legs syndrome (7.6%), parasomnia (3.5%), hypersomnia (3.5%) and sleep-related breathing disorders (1.8%). Female sex, comorbid health conditions and young adulthood seem to be risk factors for sleep disorders, but cancer-related factors were not. Differing per sleep disorder, 42–72% wanted help, but only 0–5.6% received sleep treatment. Conclusions: Insomnia and CRSD were most prevalent. An unmet need for sleep treatment was reported by childhood cancer patients during follow-up. Screening for sleep disorders after cancer might improve access to treatment and patient wellbeing. MDPI 2022-02-13 /pmc/articles/PMC8870170/ /pubmed/35205674 http://dx.doi.org/10.3390/cancers14040926 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Peersmann, Shosha H. M. Grootenhuis, Martha A. van Straten, Annemieke Kerkhof, Gerard A. Tissing, Wim J. E. Abbink, Floor de Vries, Andrica C. H. Loonen, Jacqueline Kremer, Leontien C. M. Kaspers, Gertjan J. L. van Litsenburg, Raphaële R. L. Prevalence of Sleep Disorders, Risk Factors and Sleep Treatment Needs of Adolescents and Young Adult Childhood Cancer Patients in Follow-Up after Treatment |
title | Prevalence of Sleep Disorders, Risk Factors and Sleep Treatment Needs of Adolescents and Young Adult Childhood Cancer Patients in Follow-Up after Treatment |
title_full | Prevalence of Sleep Disorders, Risk Factors and Sleep Treatment Needs of Adolescents and Young Adult Childhood Cancer Patients in Follow-Up after Treatment |
title_fullStr | Prevalence of Sleep Disorders, Risk Factors and Sleep Treatment Needs of Adolescents and Young Adult Childhood Cancer Patients in Follow-Up after Treatment |
title_full_unstemmed | Prevalence of Sleep Disorders, Risk Factors and Sleep Treatment Needs of Adolescents and Young Adult Childhood Cancer Patients in Follow-Up after Treatment |
title_short | Prevalence of Sleep Disorders, Risk Factors and Sleep Treatment Needs of Adolescents and Young Adult Childhood Cancer Patients in Follow-Up after Treatment |
title_sort | prevalence of sleep disorders, risk factors and sleep treatment needs of adolescents and young adult childhood cancer patients in follow-up after treatment |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870170/ https://www.ncbi.nlm.nih.gov/pubmed/35205674 http://dx.doi.org/10.3390/cancers14040926 |
work_keys_str_mv | AT peersmannshoshahm prevalenceofsleepdisordersriskfactorsandsleeptreatmentneedsofadolescentsandyoungadultchildhoodcancerpatientsinfollowupaftertreatment AT grootenhuismarthaa prevalenceofsleepdisordersriskfactorsandsleeptreatmentneedsofadolescentsandyoungadultchildhoodcancerpatientsinfollowupaftertreatment AT vanstratenannemieke prevalenceofsleepdisordersriskfactorsandsleeptreatmentneedsofadolescentsandyoungadultchildhoodcancerpatientsinfollowupaftertreatment AT kerkhofgerarda prevalenceofsleepdisordersriskfactorsandsleeptreatmentneedsofadolescentsandyoungadultchildhoodcancerpatientsinfollowupaftertreatment AT tissingwimje prevalenceofsleepdisordersriskfactorsandsleeptreatmentneedsofadolescentsandyoungadultchildhoodcancerpatientsinfollowupaftertreatment AT abbinkfloor prevalenceofsleepdisordersriskfactorsandsleeptreatmentneedsofadolescentsandyoungadultchildhoodcancerpatientsinfollowupaftertreatment AT devriesandricach prevalenceofsleepdisordersriskfactorsandsleeptreatmentneedsofadolescentsandyoungadultchildhoodcancerpatientsinfollowupaftertreatment AT loonenjacqueline prevalenceofsleepdisordersriskfactorsandsleeptreatmentneedsofadolescentsandyoungadultchildhoodcancerpatientsinfollowupaftertreatment AT kremerleontiencm prevalenceofsleepdisordersriskfactorsandsleeptreatmentneedsofadolescentsandyoungadultchildhoodcancerpatientsinfollowupaftertreatment AT kaspersgertjanjl prevalenceofsleepdisordersriskfactorsandsleeptreatmentneedsofadolescentsandyoungadultchildhoodcancerpatientsinfollowupaftertreatment AT vanlitsenburgraphaelerl prevalenceofsleepdisordersriskfactorsandsleeptreatmentneedsofadolescentsandyoungadultchildhoodcancerpatientsinfollowupaftertreatment |