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Interstitial Control-Released Polymer Carrying a Targeting Small-Molecule Drug Reduces PD-L1 and MGMT Expression in Recurrent High-Grade Gliomas with TMZ Resistance

SIMPLE SUMMARY: This study reports a potential new drug—Cerebraca wafer—that is designed to deliver its active pharmaceutical ingredient, (Z)-n-butylidenephthalide (BP), directly into the surgical cavity created when a brain tumor is resected. The therapeutic mechanism of Cerebraca wafer was shown t...

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Detalles Bibliográficos
Autores principales:	Liu, Ching-Ann, Liu, Wei-Hsiu, Ma, Hsin-I, Chen, Yuan-Hao, Hueng, Dueng-Yuan, Tsai, Wen-Chiuan, Lin, Shinn-Zong, Harn, Horng-Jyh, Chiou, Tzyy-Wen, Liu, Jen-Wei, Lee, Jui-Hao, Chiu, Tsung-Lang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870243/ https://www.ncbi.nlm.nih.gov/pubmed/35205800 http://dx.doi.org/10.3390/cancers14041051

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