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Response Facilitation Induced by Insulin-like Growth Factor-I in the Primary Somatosensory Cortex of Mice Was Reduced in Aging

Aging is accompanied by a decline in cognition that can be due to a lower IGF-I level. We studied response facilitation induced in primary somatosensory (S1) cortical neurons by repetitive stimulation of whiskers in young and old mice. Layer 2/3 and 5/6 neurons were extracellularly recorded in young...

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Detalles Bibliográficos
Autores principales: García-Magro, Nuria, Zegarra-Valdivia, Jonathan A., Troyas-Martinez, Sara, Torres-Aleman, Ignacio, Nuñez, Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870291/
https://www.ncbi.nlm.nih.gov/pubmed/35203366
http://dx.doi.org/10.3390/cells11040717