Proximity Ligation Mapping of Microcephaly Associated SMPD4 Shows Association with Components of the Nuclear Pore Membrane

SMPD4 is a neutral sphingomyelinase implicated in a specific type of congenital microcephaly. Although not intensively studied, SMPD4 deficiency has also been found to cause cell division defects. This suggests a role for SMPD4 in cell-cycle and differentiation. In order to explore this role, we use...

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Detalles Bibliográficos
Autores principales: Piët, Alexandra C. A., Post, Marco, Dekkers, Dick, Demmers, Jeroen A. A., Fornerod, Maarten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870324/
https://www.ncbi.nlm.nih.gov/pubmed/35203325
http://dx.doi.org/10.3390/cells11040674

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870324/
https://www.ncbi.nlm.nih.gov/pubmed/35203325
http://dx.doi.org/10.3390/cells11040674

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