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NOTCH1 Intracellular Domain and the Tumor Microenvironment as Prognostic Markers in HNSCC

SIMPLE SUMMARY: In the head and neck, a large proportion of squamous cell carcinoma demonstrate a mutation of the NOTCH1 gene. The aim of this project was to investigate the role of NOTCH1 and immunological characteristics and highlight a potential rationale for therapy. We found that a high express...

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Detalles Bibliográficos
Autores principales: Schmidl, Benedikt, Siegl, Michael, Boxberg, Melanie, Stögbauer, Fabian, Jira, Daniel, Winter, Christof, Stark, Leonhard, Pickhard, Anja, Wollenberg, Barbara, Wirth, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870336/
https://www.ncbi.nlm.nih.gov/pubmed/35205828
http://dx.doi.org/10.3390/cancers14041080