Cargando…
The Role of MeCP2 in Regulating Synaptic Plasticity in the Context of Stress and Depression
Methyl-CpG-binding protein 2 (MeCP2) is a transcriptional regulator that is highly abundant in the brain. It binds to methylated genomic DNA to regulate a range of physiological functions implicated in neuronal development and adult synaptic plasticity. MeCP2 has mainly been studied for its role in...
Autores principales: | Sánchez-Lafuente, Carla L., Kalynchuk, Lisa E., Caruncho, Hector J., Ausió, Juan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870391/ https://www.ncbi.nlm.nih.gov/pubmed/35203405 http://dx.doi.org/10.3390/cells11040748 |
Ejemplares similares
-
MeCP2 and the enigmatic organization of brain chromatin. Implications for depression and cocaine addiction
por: Ausió, Juan
Publicado: (2016) -
MeCP2: The Genetic Driver of Rett Syndrome Epigenetics
por: Good, Katrina V., et al.
Publicado: (2021) -
A Scoping Review of Rodent Studies Investigating the Epigenetic Mechanisms in the Brain Underlying the Effects of Diet on Depressive-like Behaviour
por: Sánchez-Lafuente, Carla L., et al.
Publicado: (2022) -
Circadian Cycle-Dependent MeCP2 and Brain Chromatin Changes
por: Martínez de Paz, Alexia, et al.
Publicado: (2015) -
MeCP2 post-translational modifications: a mechanism to control its involvement in synaptic plasticity and homeostasis?
por: Bellini, Elisa, et al.
Publicado: (2014)