Cargando…

CRIF1-CDK2 Interface Inhibitors Enhance Taxol Inhibition of the Lethal Triple-Negative Breast Cancer

SIMPLE SUMMARY: This study reported our most recent results for targeting triple-negative breast cancer (TNBC) with a low survival rate, using CR6-interacting factor 1–cyclin-dependent kinase 2 (CRIF1–CDK2) interface inhibitors, by inhibiting the resistance to taxol treatment. Presently, over 50% of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sang, Xiaoye, Belmessabih, Nassira, Wang, Ruixuan, Stephen, Preyesh, Lin, Sheng-Xiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870401/ https://www.ncbi.nlm.nih.gov/pubmed/35205737 http://dx.doi.org/10.3390/cancers14040989

Ejemplares similares

Role of inhibitor of yes‐associated protein 1 in triple‐negative breast cancer with taxol‐based chemoresistance
por: Li, Ying, et al.
Publicado: (2019)

Multifunctions of CRIF1 in cancers and mitochondrial dysfunction
por: Jiang, Yangzhou, et al.
Publicado: (2022)

MYC pathway activation in triple-negative breast cancer is synthetic lethal with CDK inhibition
por: Horiuchi, Dai, et al.
Publicado: (2012)

Corrigendum: Multifunctions of CRIF1 in cancers and mitochondrial dysfunction
por: Jiang, Yangzhou, et al.
Publicado: (2023)

CRIF1 Interacting with CDK2 Regulates Bone Marrow Microenvironment-Induced G0/G1 Arrest of Leukemia Cells
por: Ran, Qian, et al.
Publicado: (2014)

Human endeavor for anti-SARS-CoV-2 pharmacotherapy: A major strategy to fight the pandemic
por: Wang, Ruixuan, et al.
Publicado: (2021)

Potential Prospect of CDK4/6 Inhibitors in Triple-Negative Breast Cancer
por: Hu, Ye, et al.
Publicado: (2021)

Cardiomyocyte Specific Deletion of Crif1 Causes Mitochondrial Cardiomyopathy in Mice
por: Shin, Juhee, et al.
Publicado: (2013)

10-Gingerol Enhances the Effect of Taxol in Triple-Negative Breast Cancer via Targeting ADRB2 Signaling
por: Liang, Yuqi, et al.
Publicado: (2023)

CDK4/6 inhibitors: A potential therapeutic approach for triple negative breast cancer
por: Saleh, Lubaid, et al.
Publicado: (2021)

Capripoxvirus antibodies detection: Relationship between the two methods alpha and beta of virus neutralisation test
por: Hamidouche, Mohamed, et al.
Publicado: (2018)

Crif1 Deficiency Reduces Adipose OXPHOS Capacity and Triggers Inflammation and Insulin Resistance in Mice
por: Ryu, Min Jeong, et al.
Publicado: (2013)

CRIF1 Deficiency Increased Homocysteine Production by Disrupting Dihydrofolate Reductase Expression in Vascular Endothelial Cells
por: Lee, Ikjun, et al.
Publicado: (2021)

Targeted deletion of Crif1 in mouse epidermis impairs skin homeostasis and hair morphogenesis
por: Shin, Jung-Min, et al.
Publicado: (2017)

Efficacy and mechanism of the combination of PARP and CDK4/6 inhibitors in the treatment of triple-negative breast cancer
por: Zhu, Xiuzhi, et al.
Publicado: (2021)

Structure-Based Design of 2-Aminopurine Derivatives as CDK2 Inhibitors for Triple-Negative Breast Cancer
por: Liang, Hanzhi, et al.
Publicado: (2022)

Combination of androgen receptor inhibitor enzalutamide with the CDK4/6 inhibitor ribociclib in triple negative breast cancer cells
por: Choupani, Edris, et al.
Publicado: (2022)

Identification of Lethal Inhibitors and Inhibitor Combinations for Mono-Driver versus Multi-Driver Triple-Negative Breast Cancer Cells
por: Ku, Geng Chia, et al.
Publicado: (2022)

CRIF1 Deficiency Induces p66shc-Mediated Oxidative Stress and Endothelial Activation
por: Nagar, Harsha, et al.
Publicado: (2014)

CRIF1 deficiency suppresses endothelial cell migration via upregulation of RhoGDI2
por: Nagar, Harsha, et al.
Publicado: (2021)

Modelling a community resilience index for urban flood-prone areas of Kerala, India (CRIF)
por: Ali, Sameer, et al.
Publicado: (2022)

Synergistic effect of eribulin and CDK inhibition for the treatment of triple negative breast cancer
por: Rao, Shreyas S., et al.
Publicado: (2017)

The CDK4/6 Inhibitor Palbociclib Inhibits Estrogen-Positive and Triple Negative Breast Cancer Bone Metastasis In Vivo
por: Saleh, Lubaid, et al.
Publicado: (2023)

Identification and characterization of CHCHD1, AURKAIP1, and CRIF1 as new members of the mammalian mitochondrial ribosome
por: Koc, Emine C., et al.
Publicado: (2013)

Deficiency of Crif1 in hair follicle stem cells retards hair growth cycle in adult mice
por: Shin, Jung-Min, et al.
Publicado: (2020)

SIRT1 Activation Attenuates the Cardiac Dysfunction Induced by Endothelial Cell-Specific Deletion of CRIF1
por: Piao, Shuyu, et al.
Publicado: (2021)

Mitochondrial Dysfunction in Podocytes Caused by CRIF1 Deficiency Leads to Progressive Albuminuria and Glomerular Sclerosis in Mice
por: Na, Ki Ryang, et al.
Publicado: (2021)

Synergistic cytotoxicity of cisplatin and Taxol in overcoming Taxol resistance through the inhibition of LDHA in oral squamous cell carcinoma
por: FENG, LIN, et al.
Publicado: (2015)

Synthetic lethality of PARP and NAMPT inhibition in triple-negative breast cancer cells
por: Bajrami, Ilirjana, et al.
Publicado: (2012)

SOX9 interacts with FOXC1 to activate MYC and regulate CDK7 inhibitor sensitivity in triple-negative breast cancer
por: Tang, Lin, et al.
Publicado: (2020)

A Dual-Specificity Inhibitor Targets Polyphosphate Kinase 1 and 2 Enzymes To Attenuate Virulence of Pseudomonas aeruginosa
por: Neville, Nolan, et al.
Publicado: (2021)

Identification of highly penetrant Rb-related synthetic lethal interactions in triple negative breast cancer
por: Brough, Rachel, et al.
Publicado: (2018)

miR-1207-5p regulates the sensitivity of triple-negative breast cancer cells to Taxol treatment via the suppression of LZTS1 expression
por: Hou, Xiaoke, et al.
Publicado: (2019)

Taxol binds to cellular microtubules
Publicado: (1982)

CDK Inhibition Primes for Anti-PD-L1 Treatment in Triple-Negative Breast Cancer Models
por: Cheung, Anthony, et al.
Publicado: (2022)

Histone deacetylase inhibitor treatment induces ‘BRCAness’ and synergistic lethality with PARP inhibitor and cisplatin against human triple negative breast cancer cells
por: Ha, Kyungsoo, et al.
Publicado: (2014)

Increased lysosomal biomass is responsible for the resistance of triple-negative breast cancers to CDK4/6 inhibition
por: Fassl, Anne, et al.
Publicado: (2020)

Overexpression of miRNA-3613-3p Enhances the Sensitivity of Triple Negative Breast Cancer to CDK4/6 Inhibitor Palbociclib
por: Yu, Yuanhang, et al.
Publicado: (2020)

Systematic Analysis of the Anticancer Agent Taxol-Producing Capacity in Colletotrichum Species and Use of the Species for Taxol Production
por: Choi, Jinhee, et al.
Publicado: (2016)

Conjugation of Aspergillus flavipes Taxol with Porphyrin Increases the Anticancer Activity of Taxol and Ameliorates Its Cytotoxic Effects
por: El-Sayed, Ashraf S. A., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_qqoav17hhskteom6c216nrlppt