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Multicentre appraisal of amyotrophic lateral sclerosis biofluid biomarkers shows primacy of blood neurofilament light chain

The routine clinical integration of individualized objective markers of disease activity in those diagnosed with the neurodegenerative disorder amyotrophic lateral sclerosis is a key requirement for therapeutic development. A large, multicentre, clinic-based, longitudinal cohort was used to systemat...

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Detalles Bibliográficos
Autores principales: Thompson, Alexander G., Gray, Elizabeth, Verber, Nick, Bobeva, Yoana, Lombardi, Vittoria, Shepheard, Stephanie R., Yildiz, Ozlem, Feneberg, Emily, Farrimond, Lucy, Dharmadasa, Thanuja, Gray, Pamela, Edmond, Evan C., Scaber, Jakub, Gagliardi, Delia, Kirby, Janine, Jenkins, Thomas M., Fratta, Pietro, McDermott, Christopher J., Manohar, Sanjay G., Talbot, Kevin, Malaspina, Andrea, Shaw, Pamela J., Turner, Martin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870425/
https://www.ncbi.nlm.nih.gov/pubmed/35224491
http://dx.doi.org/10.1093/braincomms/fcac029