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Upregulation of USP22 and ABCC1 during Sorafenib Treatment of Hepatocellular Carcinoma Contribute to Development of Resistance
Sorafenib is a small molecule that blocks tumor proliferation by targeting the activity of multi-kinases for the treatment of advanced hepatocellular carcinoma (HCC). Increasing sorafenib resistance following long-term treatment is frequently encountered. Mechanisms underlying sorafenib resistance r...
Autores principales: | Chang, Yung-Sheng, Su, Chien-Wei, Chen, San-Chi, Chen, Yen-Ying, Liang, Yuh-Jin, Wu, Jaw-Ching |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870465/ https://www.ncbi.nlm.nih.gov/pubmed/35203285 http://dx.doi.org/10.3390/cells11040634 |
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