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Predictors of genomic differentiation within a hybrid taxon

Hybridization is increasingly recognized as an important evolutionary force. Novel genetic methods now enable us to address how the genomes of parental species are combined in hybrid lineages. However, we still do not know the relative importance of admixed proportions, genome architecture and local...

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Autores principales: Cuevas, Angélica, Eroukhmanoff, Fabrice, Ravinet, Mark, Sætre, Glenn-Peter, Runemark, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870489/
https://www.ncbi.nlm.nih.gov/pubmed/35148321
http://dx.doi.org/10.1371/journal.pgen.1010027
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author Cuevas, Angélica
Eroukhmanoff, Fabrice
Ravinet, Mark
Sætre, Glenn-Peter
Runemark, Anna
author_facet Cuevas, Angélica
Eroukhmanoff, Fabrice
Ravinet, Mark
Sætre, Glenn-Peter
Runemark, Anna
author_sort Cuevas, Angélica
collection PubMed
description Hybridization is increasingly recognized as an important evolutionary force. Novel genetic methods now enable us to address how the genomes of parental species are combined in hybrid lineages. However, we still do not know the relative importance of admixed proportions, genome architecture and local selection in shaping hybrid genomes. Here, we take advantage of the genetically divergent island populations of Italian sparrow on Crete, Corsica and Sicily to investigate the predictors of genomic variation within a hybrid taxon. We test if differentiation is affected by recombination rate, selection, or variation in ancestry proportions. We find that the relationship between recombination rate and differentiation is less pronounced within hybrid lineages than between the parent species, as expected if purging of minor parent ancestry in low recombination regions reduces the variation available for differentiation. In addition, we find that differentiation between islands is correlated with differences in signatures of selection in two out of three comparisons. Signatures of selection within islands are correlated across all islands, suggesting that shared selection may mould genomic differentiation. The best predictor of strong differentiation within islands is the degree of differentiation from house sparrow, and hence loci with Spanish sparrow ancestry may vary more freely. Jointly, this suggests that constraints and selection interact in shaping the genomic landscape of differentiation in this hybrid species.
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spelling pubmed-88704892022-02-25 Predictors of genomic differentiation within a hybrid taxon Cuevas, Angélica Eroukhmanoff, Fabrice Ravinet, Mark Sætre, Glenn-Peter Runemark, Anna PLoS Genet Research Article Hybridization is increasingly recognized as an important evolutionary force. Novel genetic methods now enable us to address how the genomes of parental species are combined in hybrid lineages. However, we still do not know the relative importance of admixed proportions, genome architecture and local selection in shaping hybrid genomes. Here, we take advantage of the genetically divergent island populations of Italian sparrow on Crete, Corsica and Sicily to investigate the predictors of genomic variation within a hybrid taxon. We test if differentiation is affected by recombination rate, selection, or variation in ancestry proportions. We find that the relationship between recombination rate and differentiation is less pronounced within hybrid lineages than between the parent species, as expected if purging of minor parent ancestry in low recombination regions reduces the variation available for differentiation. In addition, we find that differentiation between islands is correlated with differences in signatures of selection in two out of three comparisons. Signatures of selection within islands are correlated across all islands, suggesting that shared selection may mould genomic differentiation. The best predictor of strong differentiation within islands is the degree of differentiation from house sparrow, and hence loci with Spanish sparrow ancestry may vary more freely. Jointly, this suggests that constraints and selection interact in shaping the genomic landscape of differentiation in this hybrid species. Public Library of Science 2022-02-11 /pmc/articles/PMC8870489/ /pubmed/35148321 http://dx.doi.org/10.1371/journal.pgen.1010027 Text en © 2022 Cuevas et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Cuevas, Angélica
Eroukhmanoff, Fabrice
Ravinet, Mark
Sætre, Glenn-Peter
Runemark, Anna
Predictors of genomic differentiation within a hybrid taxon
title Predictors of genomic differentiation within a hybrid taxon
title_full Predictors of genomic differentiation within a hybrid taxon
title_fullStr Predictors of genomic differentiation within a hybrid taxon
title_full_unstemmed Predictors of genomic differentiation within a hybrid taxon
title_short Predictors of genomic differentiation within a hybrid taxon
title_sort predictors of genomic differentiation within a hybrid taxon
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870489/
https://www.ncbi.nlm.nih.gov/pubmed/35148321
http://dx.doi.org/10.1371/journal.pgen.1010027
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