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A mechanistic modeling framework reveals the key principles underlying tumor metabolism

While aerobic glycolysis, or the Warburg effect, has for a long time been considered a hallmark of tumor metabolism, recent studies have revealed a far more complex picture. Tumor cells exhibit widespread metabolic heterogeneity, not only in their presentation of the Warburg effect but also in the n...

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Detalles Bibliográficos
Autores principales: Tripathi, Shubham, Park, Jun Hyoung, Pudakalakatti, Shivanand, Bhattacharya, Pratip K., Kaipparettu, Benny Abraham, Levine, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870510/
https://www.ncbi.nlm.nih.gov/pubmed/35148308
http://dx.doi.org/10.1371/journal.pcbi.1009841