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A mechanistic modeling framework reveals the key principles underlying tumor metabolism
While aerobic glycolysis, or the Warburg effect, has for a long time been considered a hallmark of tumor metabolism, recent studies have revealed a far more complex picture. Tumor cells exhibit widespread metabolic heterogeneity, not only in their presentation of the Warburg effect but also in the n...
Autores principales: | Tripathi, Shubham, Park, Jun Hyoung, Pudakalakatti, Shivanand, Bhattacharya, Pratip K., Kaipparettu, Benny Abraham, Levine, Herbert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870510/ https://www.ncbi.nlm.nih.gov/pubmed/35148308 http://dx.doi.org/10.1371/journal.pcbi.1009841 |
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