Camptothecin effectively treats obesity in mice through GDF15 induction

Elevated circulating levels of growth differentiation factor 15 (GDF15) have been shown to reduce food intake and lower body weight through activation of hindbrain receptor glial-derived neurotrophic factor (GDNF) receptor alpha-like (GFRAL) in rodents and nonhuman primates, thus endogenous inductio...

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Detalles Bibliográficos
Autores principales: Lu, Jun Feng, Zhu, Meng Qing, Xie, Bao Cai, Shi, Xiao Chen, Liu, Huan, Zhang, Rui Xin, Xia, Bo, Wu, Jiang Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870521/
https://www.ncbi.nlm.nih.gov/pubmed/35202387
http://dx.doi.org/10.1371/journal.pbio.3001517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870521/
https://www.ncbi.nlm.nih.gov/pubmed/35202387
http://dx.doi.org/10.1371/journal.pbio.3001517

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