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Age structure in SIRD models for the COVID-19 pandemic—A case study on Italy data and effects on mortality

The COVID-19 pandemic is bringing disruptive effects on the healthcare systems, economy and social life of countries all over the world. Even though the elder portion of the population is the most severely affected by the COVID-19 disease, the counter-measures introduced so far by governments took i...

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Detalles Bibliográficos
Autores principales: Calafiore, Giuseppe Carlo, Fracastoro, Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870534/
https://www.ncbi.nlm.nih.gov/pubmed/35202438
http://dx.doi.org/10.1371/journal.pone.0264324
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author Calafiore, Giuseppe Carlo
Fracastoro, Giulia
author_facet Calafiore, Giuseppe Carlo
Fracastoro, Giulia
author_sort Calafiore, Giuseppe Carlo
collection PubMed
description The COVID-19 pandemic is bringing disruptive effects on the healthcare systems, economy and social life of countries all over the world. Even though the elder portion of the population is the most severely affected by the COVID-19 disease, the counter-measures introduced so far by governments took into little account the age structure, with restrictions that act uniformly on the population irrespectively of age. In this paper, we introduce a SIRD model with age classes for studying the impact on the epidemic evolution of lockdown policies applied heterogeneously on the different age groups of the population. The proposed model is then applied to age-stratified COVID-19 Italian data. The simulation results suggest that control measures focused to specific age groups may bring benefits in terms of reduction of the overall mortality rate.
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spelling pubmed-88705342022-02-25 Age structure in SIRD models for the COVID-19 pandemic—A case study on Italy data and effects on mortality Calafiore, Giuseppe Carlo Fracastoro, Giulia PLoS One Research Article The COVID-19 pandemic is bringing disruptive effects on the healthcare systems, economy and social life of countries all over the world. Even though the elder portion of the population is the most severely affected by the COVID-19 disease, the counter-measures introduced so far by governments took into little account the age structure, with restrictions that act uniformly on the population irrespectively of age. In this paper, we introduce a SIRD model with age classes for studying the impact on the epidemic evolution of lockdown policies applied heterogeneously on the different age groups of the population. The proposed model is then applied to age-stratified COVID-19 Italian data. The simulation results suggest that control measures focused to specific age groups may bring benefits in terms of reduction of the overall mortality rate. Public Library of Science 2022-02-24 /pmc/articles/PMC8870534/ /pubmed/35202438 http://dx.doi.org/10.1371/journal.pone.0264324 Text en © 2022 Calafiore, Fracastoro https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Calafiore, Giuseppe Carlo
Fracastoro, Giulia
Age structure in SIRD models for the COVID-19 pandemic—A case study on Italy data and effects on mortality
title Age structure in SIRD models for the COVID-19 pandemic—A case study on Italy data and effects on mortality
title_full Age structure in SIRD models for the COVID-19 pandemic—A case study on Italy data and effects on mortality
title_fullStr Age structure in SIRD models for the COVID-19 pandemic—A case study on Italy data and effects on mortality
title_full_unstemmed Age structure in SIRD models for the COVID-19 pandemic—A case study on Italy data and effects on mortality
title_short Age structure in SIRD models for the COVID-19 pandemic—A case study on Italy data and effects on mortality
title_sort age structure in sird models for the covid-19 pandemic—a case study on italy data and effects on mortality
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870534/
https://www.ncbi.nlm.nih.gov/pubmed/35202438
http://dx.doi.org/10.1371/journal.pone.0264324
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