DKK3, Downregulated in Invasive Epithelial Ovarian Cancer, Is Associated with Chemoresistance and Enhanced Paclitaxel Susceptibility via Inhibition of the β-Catenin-P-Glycoprotein Signaling Pathway

SIMPLE SUMMARY: Dickkopf-3 (DKK3) is considered a tumor suppressor as it possesses anti-tumoral properties and is frequently downregulated in various cancers. However, the role of DKK3 in ovarian cancer is not known. In this study, we showed that DKK3 loss occurred in 56.1% of patients with ovarian...

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Autores principales: Nguyen, Que Thanh Thanh, Park, Hwang Shin, Lee, Tae Jin, Choi, Kyung-Mi, Park, Joong Yull, Kim, Daehan, Kim, Jae Hyung, Park, Junsoo, Lee, Eun-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870560/
https://www.ncbi.nlm.nih.gov/pubmed/35205672
http://dx.doi.org/10.3390/cancers14040924

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