Prevention of L-Dopa-Induced Dyskinesias by MPEP Blockade of Metabotropic Glutamate Receptor 5 Is Associated with Reduced Inflammation in the Brain of Parkinsonian Monkeys

Proinflammatory markers were found in brains of Parkinson’s disease (PD) patients. After years of L-Dopa symptomatic treatment, most PD patients develop dyskinesias. The relationship between inflammation and L-Dopa-induced dyskinesias (LID) is still unclear. We previously reported that MPEP (a metab...

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Detalles Bibliográficos
Autores principales: Morissette, Marc, Bourque, Mélanie, Tremblay, Marie-Ève, Di Paolo, Thérèse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870609/
https://www.ncbi.nlm.nih.gov/pubmed/35203338
http://dx.doi.org/10.3390/cells11040691

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