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Epigenetic Dysregulation of the Homeobox A5 (HOXA5) Gene Associates with Subcutaneous Adipocyte Hypertrophy in Human Obesity
Along with insulin resistance and increased risk of type 2 diabetes (T2D), lean first-degree relatives of T2D subjects (FDR) feature impaired adipogenesis in subcutaneous adipose tissue (SAT) and subcutaneous adipocyte hypertrophy well before diabetes onset. The molecular mechanisms linking these ev...
Autores principales: | Parrillo, Luca, Spinelli, Rosa, Costanzo, Mattia, Florese, Pasqualina, Cabaro, Serena, Desiderio, Antonella, Prevenzano, Immacolata, Raciti, Gregory Alexander, Smith, Ulf, Miele, Claudia, Formisano, Pietro, Napoli, Raffaele, Beguinot, Francesco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870634/ https://www.ncbi.nlm.nih.gov/pubmed/35203377 http://dx.doi.org/10.3390/cells11040728 |
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