Cargando…

Calcineurin Controls Cellular Prion Protein Expression in Mouse Astrocytes

Prion diseases arise from the conformational conversion of the cellular prion protein (PrP(C)) into a self-replicating prion isoform (PrP(Sc)). Although this process has been studied mostly in neurons, a growing body of evidence suggests that astrocytes express PrP(C) and are able to replicate and a...

Descripción completa

Detalles Bibliográficos
Autores principales: Dematteis, Giulia, Restelli, Elena, Vanella, Virginia Vita, Manfredi, Marcello, Marengo, Emilio, Corazzari, Marco, Genazzani, Armando A., Chiesa, Roberto, Lim, Dmitry, Tapella, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870693/
https://www.ncbi.nlm.nih.gov/pubmed/35203261
http://dx.doi.org/10.3390/cells11040609