Multimodal Characterization of a PSMA-Positive Thyroid Nodule Using (68)Ga-PSMA and (124)Iodine PET/US Fusion Imaging

A 54-year-old male diagnosed with prostate cancer was referred for (68)Gallium-PSMA-11 PET/CT. The scan revealed a solitary PSMA-positive thyroid lesion. On PET/ultrasound fusion imaging, a nodule with moderate risk of malignancy (TIRADS 4B) could be unambiguously correlated. Additional (124)Iodine...

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Autores principales: Freesmeyer, Martin, Gühne, Falk, Drescher, Robert, Winkens, Thomas, Gassler, Nikolaus, Seifert, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Interesting Images
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870750/
https://www.ncbi.nlm.nih.gov/pubmed/35204563
http://dx.doi.org/10.3390/diagnostics12020472
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author Freesmeyer, Martin
Gühne, Falk
Drescher, Robert
Winkens, Thomas
Gassler, Nikolaus
Seifert, Philipp
author_facet Freesmeyer, Martin
Gühne, Falk
Drescher, Robert
Winkens, Thomas
Gassler, Nikolaus
Seifert, Philipp
author_sort Freesmeyer, Martin
collection PubMed
description A 54-year-old male diagnosed with prostate cancer was referred for (68)Gallium-PSMA-11 PET/CT. The scan revealed a solitary PSMA-positive thyroid lesion. On PET/ultrasound fusion imaging, a nodule with moderate risk of malignancy (TIRADS 4B) could be unambiguously correlated. Additional (124)Iodine PET/ultrasound fusion imaging revealed normal iodine uptake within the PSMA-positive thyroid nodule. Fine-needle aspiration cytology was performed using an ultrasound needle-guidance system. The cytopathological investigation confirmed a benign thyroid nodule and excluded a thyroid carcinoma as well as a prostate cancer metastasis. Immunohistochemistry was positive for thyroglobulin staining.
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spelling pubmed-88707502022-02-25 Multimodal Characterization of a PSMA-Positive Thyroid Nodule Using (68)Ga-PSMA and (124)Iodine PET/US Fusion Imaging Freesmeyer, Martin Gühne, Falk Drescher, Robert Winkens, Thomas Gassler, Nikolaus Seifert, Philipp Diagnostics (Basel) Interesting Images A 54-year-old male diagnosed with prostate cancer was referred for (68)Gallium-PSMA-11 PET/CT. The scan revealed a solitary PSMA-positive thyroid lesion. On PET/ultrasound fusion imaging, a nodule with moderate risk of malignancy (TIRADS 4B) could be unambiguously correlated. Additional (124)Iodine PET/ultrasound fusion imaging revealed normal iodine uptake within the PSMA-positive thyroid nodule. Fine-needle aspiration cytology was performed using an ultrasound needle-guidance system. The cytopathological investigation confirmed a benign thyroid nodule and excluded a thyroid carcinoma as well as a prostate cancer metastasis. Immunohistochemistry was positive for thyroglobulin staining. MDPI 2022-02-12 /pmc/articles/PMC8870750/ /pubmed/35204563 http://dx.doi.org/10.3390/diagnostics12020472 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Interesting Images
Freesmeyer, Martin
Gühne, Falk
Drescher, Robert
Winkens, Thomas
Gassler, Nikolaus
Seifert, Philipp
Multimodal Characterization of a PSMA-Positive Thyroid Nodule Using (68)Ga-PSMA and (124)Iodine PET/US Fusion Imaging
title Multimodal Characterization of a PSMA-Positive Thyroid Nodule Using (68)Ga-PSMA and (124)Iodine PET/US Fusion Imaging
title_full Multimodal Characterization of a PSMA-Positive Thyroid Nodule Using (68)Ga-PSMA and (124)Iodine PET/US Fusion Imaging
title_fullStr Multimodal Characterization of a PSMA-Positive Thyroid Nodule Using (68)Ga-PSMA and (124)Iodine PET/US Fusion Imaging
title_full_unstemmed Multimodal Characterization of a PSMA-Positive Thyroid Nodule Using (68)Ga-PSMA and (124)Iodine PET/US Fusion Imaging
title_short Multimodal Characterization of a PSMA-Positive Thyroid Nodule Using (68)Ga-PSMA and (124)Iodine PET/US Fusion Imaging
title_sort multimodal characterization of a psma-positive thyroid nodule using (68)ga-psma and (124)iodine pet/us fusion imaging
topic Interesting Images
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870750/
https://www.ncbi.nlm.nih.gov/pubmed/35204563
http://dx.doi.org/10.3390/diagnostics12020472
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