A Rare Case of Radiation-Induced Liver Disease in Treated Abdominal Lymphoma Showing High [(18)F]FDG Avidity and Low EOB Uptake Proportional to the Irradiation Dose

A 44-year-old woman presented with high [(18)F]FDG uptake liver lesion after six courses of R-CHOP and radiotherapy for abdominal DLBCL, which was misdiagnosed as a hepatic invasion. EOB–MRI showed slight T2 hyperintensity, low-intensity DWI, and decreased EOB uptake in the hepatocellular phase. Com...

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Detalles Bibliográficos
Autores principales: Usami, Aya, Yokoyama, Kota, Tsuchiya, Junichi, Umezawa, Yoshihiro, Toda, Kazuma, Tateishi, Ukihide, Yoshimura, Ryoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870758/
https://www.ncbi.nlm.nih.gov/pubmed/35204594
http://dx.doi.org/10.3390/diagnostics12020504
Descripción
Sumario:A 44-year-old woman presented with high [(18)F]FDG uptake liver lesion after six courses of R-CHOP and radiotherapy for abdominal DLBCL, which was misdiagnosed as a hepatic invasion. EOB–MRI showed slight T2 hyperintensity, low-intensity DWI, and decreased EOB uptake in the hepatocellular phase. Compared with the pretreatment planning CT, the liver lesion coincided with the area of >40.5 Gy, resulting in the diagnosis of RILD. At the follow-up [(18)F]FDG PET/CT 7 months after irradiation, the abnormal liver uptake disappeared. Comparing [(18)F]FDG PET/CT, EOB–MRI, and planning CT can lead to the correct diagnosis of RILD and avoid unnecessary biopsies and treatment changes.

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