A Rare Case of Radiation-Induced Liver Disease in Treated Abdominal Lymphoma Showing High [(18)F]FDG Avidity and Low EOB Uptake Proportional to the Irradiation Dose

A 44-year-old woman presented with high [(18)F]FDG uptake liver lesion after six courses of R-CHOP and radiotherapy for abdominal DLBCL, which was misdiagnosed as a hepatic invasion. EOB–MRI showed slight T2 hyperintensity, low-intensity DWI, and decreased EOB uptake in the hepatocellular phase. Com...

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Autores principales: Usami, Aya, Yokoyama, Kota, Tsuchiya, Junichi, Umezawa, Yoshihiro, Toda, Kazuma, Tateishi, Ukihide, Yoshimura, Ryoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Interesting Images
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870758/
https://www.ncbi.nlm.nih.gov/pubmed/35204594
http://dx.doi.org/10.3390/diagnostics12020504
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author Usami, Aya
Yokoyama, Kota
Tsuchiya, Junichi
Umezawa, Yoshihiro
Toda, Kazuma
Tateishi, Ukihide
Yoshimura, Ryoichi
author_facet Usami, Aya
Yokoyama, Kota
Tsuchiya, Junichi
Umezawa, Yoshihiro
Toda, Kazuma
Tateishi, Ukihide
Yoshimura, Ryoichi
author_sort Usami, Aya
collection PubMed
description A 44-year-old woman presented with high [(18)F]FDG uptake liver lesion after six courses of R-CHOP and radiotherapy for abdominal DLBCL, which was misdiagnosed as a hepatic invasion. EOB–MRI showed slight T2 hyperintensity, low-intensity DWI, and decreased EOB uptake in the hepatocellular phase. Compared with the pretreatment planning CT, the liver lesion coincided with the area of >40.5 Gy, resulting in the diagnosis of RILD. At the follow-up [(18)F]FDG PET/CT 7 months after irradiation, the abnormal liver uptake disappeared. Comparing [(18)F]FDG PET/CT, EOB–MRI, and planning CT can lead to the correct diagnosis of RILD and avoid unnecessary biopsies and treatment changes.
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spelling pubmed-88707582022-02-25 A Rare Case of Radiation-Induced Liver Disease in Treated Abdominal Lymphoma Showing High [(18)F]FDG Avidity and Low EOB Uptake Proportional to the Irradiation Dose Usami, Aya Yokoyama, Kota Tsuchiya, Junichi Umezawa, Yoshihiro Toda, Kazuma Tateishi, Ukihide Yoshimura, Ryoichi Diagnostics (Basel) Interesting Images A 44-year-old woman presented with high [(18)F]FDG uptake liver lesion after six courses of R-CHOP and radiotherapy for abdominal DLBCL, which was misdiagnosed as a hepatic invasion. EOB–MRI showed slight T2 hyperintensity, low-intensity DWI, and decreased EOB uptake in the hepatocellular phase. Compared with the pretreatment planning CT, the liver lesion coincided with the area of >40.5 Gy, resulting in the diagnosis of RILD. At the follow-up [(18)F]FDG PET/CT 7 months after irradiation, the abnormal liver uptake disappeared. Comparing [(18)F]FDG PET/CT, EOB–MRI, and planning CT can lead to the correct diagnosis of RILD and avoid unnecessary biopsies and treatment changes. MDPI 2022-02-16 /pmc/articles/PMC8870758/ /pubmed/35204594 http://dx.doi.org/10.3390/diagnostics12020504 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Interesting Images
Usami, Aya
Yokoyama, Kota
Tsuchiya, Junichi
Umezawa, Yoshihiro
Toda, Kazuma
Tateishi, Ukihide
Yoshimura, Ryoichi
A Rare Case of Radiation-Induced Liver Disease in Treated Abdominal Lymphoma Showing High [(18)F]FDG Avidity and Low EOB Uptake Proportional to the Irradiation Dose
title A Rare Case of Radiation-Induced Liver Disease in Treated Abdominal Lymphoma Showing High [(18)F]FDG Avidity and Low EOB Uptake Proportional to the Irradiation Dose
title_full A Rare Case of Radiation-Induced Liver Disease in Treated Abdominal Lymphoma Showing High [(18)F]FDG Avidity and Low EOB Uptake Proportional to the Irradiation Dose
title_fullStr A Rare Case of Radiation-Induced Liver Disease in Treated Abdominal Lymphoma Showing High [(18)F]FDG Avidity and Low EOB Uptake Proportional to the Irradiation Dose
title_full_unstemmed A Rare Case of Radiation-Induced Liver Disease in Treated Abdominal Lymphoma Showing High [(18)F]FDG Avidity and Low EOB Uptake Proportional to the Irradiation Dose
title_short A Rare Case of Radiation-Induced Liver Disease in Treated Abdominal Lymphoma Showing High [(18)F]FDG Avidity and Low EOB Uptake Proportional to the Irradiation Dose
title_sort rare case of radiation-induced liver disease in treated abdominal lymphoma showing high [(18)f]fdg avidity and low eob uptake proportional to the irradiation dose
topic Interesting Images
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870758/
https://www.ncbi.nlm.nih.gov/pubmed/35204594
http://dx.doi.org/10.3390/diagnostics12020504
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