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Unexpected Sex Differences in the Relationship of Sacroiliac Joint and Lumbar Spine Degeneration

The relationship between degenerative changes of the sacroiliac joints and the lumbar spine on CT has not been studied yet. The aim of this analysis is to determine the nature of their association as well as the influence of fixed anatomical spinopelvic parameters on sacroiliac joint degeneration. F...

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Autores principales: Muellner, Maximilian, Kreutzinger, Virginie, Becker, Luis, Diekhoff, Torsten, Pumberger, Matthias, Schömig, Friederike, Heyland, Mark, Ziegeler, Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870885/
https://www.ncbi.nlm.nih.gov/pubmed/35204366
http://dx.doi.org/10.3390/diagnostics12020275
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author Muellner, Maximilian
Kreutzinger, Virginie
Becker, Luis
Diekhoff, Torsten
Pumberger, Matthias
Schömig, Friederike
Heyland, Mark
Ziegeler, Katharina
author_facet Muellner, Maximilian
Kreutzinger, Virginie
Becker, Luis
Diekhoff, Torsten
Pumberger, Matthias
Schömig, Friederike
Heyland, Mark
Ziegeler, Katharina
author_sort Muellner, Maximilian
collection PubMed
description The relationship between degenerative changes of the sacroiliac joints and the lumbar spine on CT has not been studied yet. The aim of this analysis is to determine the nature of their association as well as the influence of fixed anatomical spinopelvic parameters on sacroiliac joint degeneration. For this institutional review-board-approved investigation, imaging datasets as well as electronic medical records of 719 patients without back pain from the clinical routine of our department of radiology were included. Age, sex, weight category (slim, normal, obese), parity in women and indication for imaging were noted for all patients. The presence of degenerative lesions of the lumbar spine (disc degeneration, endplate degeneration, spondylophytes, and facet joint osteoarthritis) was noted separately at each lumbar segment (L1 to L5). Sacroiliac joints were assessed for sclerosis and osteophytes. Fixed anatomical spinopelvic parameters were measured: pelvic radius = PR; pelvic incidence = PI; sacral table angle = STA. Correlation as well as regression analyses were performed; data were analyzed for males and females separately. PI increased significantly with age in both women and men, while STA decreased and PR remained constant; neither of them was associated with SIJ degeneration. SIJ degeneration correlated with disc degeneration (tau = 0.331; p < 0.001), spondylophytes (tau = 0.397; p < 0.001), and facet joint degeneration (tau = 0.310; p < 0.001) in men, but with no parameter of spinal degeneration in women. Lumbar spinal degeneration increased the risk of sacroiliac joint degeneration in men significantly (OR 7.2; 95%CI 2.8–19.0), but it was not a significant covariable in women. Fixed spinopelvic parameters have little impact on sacroiliac joint degeneration. The degeneration of the sacroiliac joints and the lumbar spine appear to be parallel processes in men, but are largely unrelated in women.
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spelling pubmed-88708852022-02-25 Unexpected Sex Differences in the Relationship of Sacroiliac Joint and Lumbar Spine Degeneration Muellner, Maximilian Kreutzinger, Virginie Becker, Luis Diekhoff, Torsten Pumberger, Matthias Schömig, Friederike Heyland, Mark Ziegeler, Katharina Diagnostics (Basel) Article The relationship between degenerative changes of the sacroiliac joints and the lumbar spine on CT has not been studied yet. The aim of this analysis is to determine the nature of their association as well as the influence of fixed anatomical spinopelvic parameters on sacroiliac joint degeneration. For this institutional review-board-approved investigation, imaging datasets as well as electronic medical records of 719 patients without back pain from the clinical routine of our department of radiology were included. Age, sex, weight category (slim, normal, obese), parity in women and indication for imaging were noted for all patients. The presence of degenerative lesions of the lumbar spine (disc degeneration, endplate degeneration, spondylophytes, and facet joint osteoarthritis) was noted separately at each lumbar segment (L1 to L5). Sacroiliac joints were assessed for sclerosis and osteophytes. Fixed anatomical spinopelvic parameters were measured: pelvic radius = PR; pelvic incidence = PI; sacral table angle = STA. Correlation as well as regression analyses were performed; data were analyzed for males and females separately. PI increased significantly with age in both women and men, while STA decreased and PR remained constant; neither of them was associated with SIJ degeneration. SIJ degeneration correlated with disc degeneration (tau = 0.331; p < 0.001), spondylophytes (tau = 0.397; p < 0.001), and facet joint degeneration (tau = 0.310; p < 0.001) in men, but with no parameter of spinal degeneration in women. Lumbar spinal degeneration increased the risk of sacroiliac joint degeneration in men significantly (OR 7.2; 95%CI 2.8–19.0), but it was not a significant covariable in women. Fixed spinopelvic parameters have little impact on sacroiliac joint degeneration. The degeneration of the sacroiliac joints and the lumbar spine appear to be parallel processes in men, but are largely unrelated in women. MDPI 2022-01-21 /pmc/articles/PMC8870885/ /pubmed/35204366 http://dx.doi.org/10.3390/diagnostics12020275 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Muellner, Maximilian
Kreutzinger, Virginie
Becker, Luis
Diekhoff, Torsten
Pumberger, Matthias
Schömig, Friederike
Heyland, Mark
Ziegeler, Katharina
Unexpected Sex Differences in the Relationship of Sacroiliac Joint and Lumbar Spine Degeneration
title Unexpected Sex Differences in the Relationship of Sacroiliac Joint and Lumbar Spine Degeneration
title_full Unexpected Sex Differences in the Relationship of Sacroiliac Joint and Lumbar Spine Degeneration
title_fullStr Unexpected Sex Differences in the Relationship of Sacroiliac Joint and Lumbar Spine Degeneration
title_full_unstemmed Unexpected Sex Differences in the Relationship of Sacroiliac Joint and Lumbar Spine Degeneration
title_short Unexpected Sex Differences in the Relationship of Sacroiliac Joint and Lumbar Spine Degeneration
title_sort unexpected sex differences in the relationship of sacroiliac joint and lumbar spine degeneration
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870885/
https://www.ncbi.nlm.nih.gov/pubmed/35204366
http://dx.doi.org/10.3390/diagnostics12020275
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