Specifically Regional Cerebral Hypoperfusion in a Case of Highly Suspected Sporadic Creutzfeldt-Jakob Disease on (99m)Tc-ECD SPECT/CT with Easy Z-Score Imaging System Analysis

Sporadic Creutzfeldt-Jakob disease (sCJD) is a rapidly-progressive dementing illness, the challenge of diagnosis during life. We presented a 78-year-old woman reported stupor, right facial palsy, and fluctuations in consciousness. (99m)Tc-ECD brain SPECT/CT with eZIS analysis revealed significant de...

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Detalles Bibliográficos
Autores principales: Chen, Shun-Chieh, Shen, Daniel Hueng-Yuan, Chan, Hung-Yen, Yang, Ming-Hui, Chan, Hung-Pin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870892/
https://www.ncbi.nlm.nih.gov/pubmed/35204527
http://dx.doi.org/10.3390/diagnostics12020437
Descripción
Sumario:Sporadic Creutzfeldt-Jakob disease (sCJD) is a rapidly-progressive dementing illness, the challenge of diagnosis during life. We presented a 78-year-old woman reported stupor, right facial palsy, and fluctuations in consciousness. (99m)Tc-ECD brain SPECT/CT with eZIS analysis revealed significant decreased regional cerebral blood flow mainly in specific regions of Alzheimer’s disease as the published article reported with involving frontal region. Brain DWI MRI increased signal intensities corresponding to similar location of (99m)Tc-ECD brain SPECT/CT. In this case, we reported the pattern of decreased rCBF may correlate to rapidly progressive dementia and associated neurodegenerative symptoms of the highly suspected sCJD patient.

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