Specifically Regional Cerebral Hypoperfusion in a Case of Highly Suspected Sporadic Creutzfeldt-Jakob Disease on (99m)Tc-ECD SPECT/CT with Easy Z-Score Imaging System Analysis

Sporadic Creutzfeldt-Jakob disease (sCJD) is a rapidly-progressive dementing illness, the challenge of diagnosis during life. We presented a 78-year-old woman reported stupor, right facial palsy, and fluctuations in consciousness. (99m)Tc-ECD brain SPECT/CT with eZIS analysis revealed significant de...

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Autores principales: Chen, Shun-Chieh, Shen, Daniel Hueng-Yuan, Chan, Hung-Yen, Yang, Ming-Hui, Chan, Hung-Pin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Interesting Images
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870892/
https://www.ncbi.nlm.nih.gov/pubmed/35204527
http://dx.doi.org/10.3390/diagnostics12020437
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author Chen, Shun-Chieh
Shen, Daniel Hueng-Yuan
Chan, Hung-Yen
Yang, Ming-Hui
Chan, Hung-Pin
author_facet Chen, Shun-Chieh
Shen, Daniel Hueng-Yuan
Chan, Hung-Yen
Yang, Ming-Hui
Chan, Hung-Pin
author_sort Chen, Shun-Chieh
collection PubMed
description Sporadic Creutzfeldt-Jakob disease (sCJD) is a rapidly-progressive dementing illness, the challenge of diagnosis during life. We presented a 78-year-old woman reported stupor, right facial palsy, and fluctuations in consciousness. (99m)Tc-ECD brain SPECT/CT with eZIS analysis revealed significant decreased regional cerebral blood flow mainly in specific regions of Alzheimer’s disease as the published article reported with involving frontal region. Brain DWI MRI increased signal intensities corresponding to similar location of (99m)Tc-ECD brain SPECT/CT. In this case, we reported the pattern of decreased rCBF may correlate to rapidly progressive dementia and associated neurodegenerative symptoms of the highly suspected sCJD patient.
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spelling pubmed-88708922022-02-25 Specifically Regional Cerebral Hypoperfusion in a Case of Highly Suspected Sporadic Creutzfeldt-Jakob Disease on (99m)Tc-ECD SPECT/CT with Easy Z-Score Imaging System Analysis Chen, Shun-Chieh Shen, Daniel Hueng-Yuan Chan, Hung-Yen Yang, Ming-Hui Chan, Hung-Pin Diagnostics (Basel) Interesting Images Sporadic Creutzfeldt-Jakob disease (sCJD) is a rapidly-progressive dementing illness, the challenge of diagnosis during life. We presented a 78-year-old woman reported stupor, right facial palsy, and fluctuations in consciousness. (99m)Tc-ECD brain SPECT/CT with eZIS analysis revealed significant decreased regional cerebral blood flow mainly in specific regions of Alzheimer’s disease as the published article reported with involving frontal region. Brain DWI MRI increased signal intensities corresponding to similar location of (99m)Tc-ECD brain SPECT/CT. In this case, we reported the pattern of decreased rCBF may correlate to rapidly progressive dementia and associated neurodegenerative symptoms of the highly suspected sCJD patient. MDPI 2022-02-08 /pmc/articles/PMC8870892/ /pubmed/35204527 http://dx.doi.org/10.3390/diagnostics12020437 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Interesting Images
Chen, Shun-Chieh
Shen, Daniel Hueng-Yuan
Chan, Hung-Yen
Yang, Ming-Hui
Chan, Hung-Pin
Specifically Regional Cerebral Hypoperfusion in a Case of Highly Suspected Sporadic Creutzfeldt-Jakob Disease on (99m)Tc-ECD SPECT/CT with Easy Z-Score Imaging System Analysis
title Specifically Regional Cerebral Hypoperfusion in a Case of Highly Suspected Sporadic Creutzfeldt-Jakob Disease on (99m)Tc-ECD SPECT/CT with Easy Z-Score Imaging System Analysis
title_full Specifically Regional Cerebral Hypoperfusion in a Case of Highly Suspected Sporadic Creutzfeldt-Jakob Disease on (99m)Tc-ECD SPECT/CT with Easy Z-Score Imaging System Analysis
title_fullStr Specifically Regional Cerebral Hypoperfusion in a Case of Highly Suspected Sporadic Creutzfeldt-Jakob Disease on (99m)Tc-ECD SPECT/CT with Easy Z-Score Imaging System Analysis
title_full_unstemmed Specifically Regional Cerebral Hypoperfusion in a Case of Highly Suspected Sporadic Creutzfeldt-Jakob Disease on (99m)Tc-ECD SPECT/CT with Easy Z-Score Imaging System Analysis
title_short Specifically Regional Cerebral Hypoperfusion in a Case of Highly Suspected Sporadic Creutzfeldt-Jakob Disease on (99m)Tc-ECD SPECT/CT with Easy Z-Score Imaging System Analysis
title_sort specifically regional cerebral hypoperfusion in a case of highly suspected sporadic creutzfeldt-jakob disease on (99m)tc-ecd spect/ct with easy z-score imaging system analysis
topic Interesting Images
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870892/
https://www.ncbi.nlm.nih.gov/pubmed/35204527
http://dx.doi.org/10.3390/diagnostics12020437
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