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Simulation of Cardiac Flow under the Septal Defect Based on Lattice Boltzmann Method

In this paper, the lattice Boltzmann method was used to simulate the cardiac flow in children with aseptal defect. The inner wall model of the heart was reconstructed from 210 computed tomography scans. By simulating and comparing the cardiac flow field, the pressure field, the blood oxygen content,...

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Detalles Bibliográficos
Autores principales: Wang, Zhengdao, Zhang, Xiandong, Li, Yumeng, Yang, Hui, Xue, Haihong, Wei, Yikun, Qian, Yuehong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871033/
https://www.ncbi.nlm.nih.gov/pubmed/35205482
http://dx.doi.org/10.3390/e24020187
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author Wang, Zhengdao
Zhang, Xiandong
Li, Yumeng
Yang, Hui
Xue, Haihong
Wei, Yikun
Qian, Yuehong
author_facet Wang, Zhengdao
Zhang, Xiandong
Li, Yumeng
Yang, Hui
Xue, Haihong
Wei, Yikun
Qian, Yuehong
author_sort Wang, Zhengdao
collection PubMed
description In this paper, the lattice Boltzmann method was used to simulate the cardiac flow in children with aseptal defect. The inner wall model of the heart was reconstructed from 210 computed tomography scans. By simulating and comparing the cardiac flow field, the pressure field, the blood oxygen content, and the distribution of entropy generation before and after an operation, the effects of septal defect on pulmonary hypertension(PH), cyanosis, and heart load were analyzed in detail. It is found that the atrial septal defect(ASD) of the child we analyzed had a great influence on the blood oxygen content in the pulmonary artery, which leads to lower efficiency of oxygen binding in the lungs and increases the burden on the heart. At the same time, it also significantly enhanced the entropy generation rate of the cardiac flow, which also leads to a higher heart load. However, the main cause of PH is not ASD, but ventricular septal defect (VSD). Meanwhile, it significantly reduced the blood oxygen content in the brachiocephalic trunk, but rarely affects the blood oxygen contents in the downstream left common carotid artery, left subclavian artery, and descending aorta are not significantly affected by VSD. It causes severe cyanosis on the face and lips.
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spelling pubmed-88710332022-02-25 Simulation of Cardiac Flow under the Septal Defect Based on Lattice Boltzmann Method Wang, Zhengdao Zhang, Xiandong Li, Yumeng Yang, Hui Xue, Haihong Wei, Yikun Qian, Yuehong Entropy (Basel) Article In this paper, the lattice Boltzmann method was used to simulate the cardiac flow in children with aseptal defect. The inner wall model of the heart was reconstructed from 210 computed tomography scans. By simulating and comparing the cardiac flow field, the pressure field, the blood oxygen content, and the distribution of entropy generation before and after an operation, the effects of septal defect on pulmonary hypertension(PH), cyanosis, and heart load were analyzed in detail. It is found that the atrial septal defect(ASD) of the child we analyzed had a great influence on the blood oxygen content in the pulmonary artery, which leads to lower efficiency of oxygen binding in the lungs and increases the burden on the heart. At the same time, it also significantly enhanced the entropy generation rate of the cardiac flow, which also leads to a higher heart load. However, the main cause of PH is not ASD, but ventricular septal defect (VSD). Meanwhile, it significantly reduced the blood oxygen content in the brachiocephalic trunk, but rarely affects the blood oxygen contents in the downstream left common carotid artery, left subclavian artery, and descending aorta are not significantly affected by VSD. It causes severe cyanosis on the face and lips. MDPI 2022-01-27 /pmc/articles/PMC8871033/ /pubmed/35205482 http://dx.doi.org/10.3390/e24020187 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Wang, Zhengdao
Zhang, Xiandong
Li, Yumeng
Yang, Hui
Xue, Haihong
Wei, Yikun
Qian, Yuehong
Simulation of Cardiac Flow under the Septal Defect Based on Lattice Boltzmann Method
title Simulation of Cardiac Flow under the Septal Defect Based on Lattice Boltzmann Method
title_full Simulation of Cardiac Flow under the Septal Defect Based on Lattice Boltzmann Method
title_fullStr Simulation of Cardiac Flow under the Septal Defect Based on Lattice Boltzmann Method
title_full_unstemmed Simulation of Cardiac Flow under the Septal Defect Based on Lattice Boltzmann Method
title_short Simulation of Cardiac Flow under the Septal Defect Based on Lattice Boltzmann Method
title_sort simulation of cardiac flow under the septal defect based on lattice boltzmann method
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871033/
https://www.ncbi.nlm.nih.gov/pubmed/35205482
http://dx.doi.org/10.3390/e24020187
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