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Simulation of Cardiac Flow under the Septal Defect Based on Lattice Boltzmann Method
In this paper, the lattice Boltzmann method was used to simulate the cardiac flow in children with aseptal defect. The inner wall model of the heart was reconstructed from 210 computed tomography scans. By simulating and comparing the cardiac flow field, the pressure field, the blood oxygen content,...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871033/ https://www.ncbi.nlm.nih.gov/pubmed/35205482 http://dx.doi.org/10.3390/e24020187 |
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author | Wang, Zhengdao Zhang, Xiandong Li, Yumeng Yang, Hui Xue, Haihong Wei, Yikun Qian, Yuehong |
author_facet | Wang, Zhengdao Zhang, Xiandong Li, Yumeng Yang, Hui Xue, Haihong Wei, Yikun Qian, Yuehong |
author_sort | Wang, Zhengdao |
collection | PubMed |
description | In this paper, the lattice Boltzmann method was used to simulate the cardiac flow in children with aseptal defect. The inner wall model of the heart was reconstructed from 210 computed tomography scans. By simulating and comparing the cardiac flow field, the pressure field, the blood oxygen content, and the distribution of entropy generation before and after an operation, the effects of septal defect on pulmonary hypertension(PH), cyanosis, and heart load were analyzed in detail. It is found that the atrial septal defect(ASD) of the child we analyzed had a great influence on the blood oxygen content in the pulmonary artery, which leads to lower efficiency of oxygen binding in the lungs and increases the burden on the heart. At the same time, it also significantly enhanced the entropy generation rate of the cardiac flow, which also leads to a higher heart load. However, the main cause of PH is not ASD, but ventricular septal defect (VSD). Meanwhile, it significantly reduced the blood oxygen content in the brachiocephalic trunk, but rarely affects the blood oxygen contents in the downstream left common carotid artery, left subclavian artery, and descending aorta are not significantly affected by VSD. It causes severe cyanosis on the face and lips. |
format | Online Article Text |
id | pubmed-8871033 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-88710332022-02-25 Simulation of Cardiac Flow under the Septal Defect Based on Lattice Boltzmann Method Wang, Zhengdao Zhang, Xiandong Li, Yumeng Yang, Hui Xue, Haihong Wei, Yikun Qian, Yuehong Entropy (Basel) Article In this paper, the lattice Boltzmann method was used to simulate the cardiac flow in children with aseptal defect. The inner wall model of the heart was reconstructed from 210 computed tomography scans. By simulating and comparing the cardiac flow field, the pressure field, the blood oxygen content, and the distribution of entropy generation before and after an operation, the effects of septal defect on pulmonary hypertension(PH), cyanosis, and heart load were analyzed in detail. It is found that the atrial septal defect(ASD) of the child we analyzed had a great influence on the blood oxygen content in the pulmonary artery, which leads to lower efficiency of oxygen binding in the lungs and increases the burden on the heart. At the same time, it also significantly enhanced the entropy generation rate of the cardiac flow, which also leads to a higher heart load. However, the main cause of PH is not ASD, but ventricular septal defect (VSD). Meanwhile, it significantly reduced the blood oxygen content in the brachiocephalic trunk, but rarely affects the blood oxygen contents in the downstream left common carotid artery, left subclavian artery, and descending aorta are not significantly affected by VSD. It causes severe cyanosis on the face and lips. MDPI 2022-01-27 /pmc/articles/PMC8871033/ /pubmed/35205482 http://dx.doi.org/10.3390/e24020187 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Wang, Zhengdao Zhang, Xiandong Li, Yumeng Yang, Hui Xue, Haihong Wei, Yikun Qian, Yuehong Simulation of Cardiac Flow under the Septal Defect Based on Lattice Boltzmann Method |
title | Simulation of Cardiac Flow under the Septal Defect Based on Lattice Boltzmann Method |
title_full | Simulation of Cardiac Flow under the Septal Defect Based on Lattice Boltzmann Method |
title_fullStr | Simulation of Cardiac Flow under the Septal Defect Based on Lattice Boltzmann Method |
title_full_unstemmed | Simulation of Cardiac Flow under the Septal Defect Based on Lattice Boltzmann Method |
title_short | Simulation of Cardiac Flow under the Septal Defect Based on Lattice Boltzmann Method |
title_sort | simulation of cardiac flow under the septal defect based on lattice boltzmann method |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871033/ https://www.ncbi.nlm.nih.gov/pubmed/35205482 http://dx.doi.org/10.3390/e24020187 |
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