Short-chain fatty acid acetate triggers antiviral response mediated by RIG-I in cells from infants with respiratory syncytial virus bronchiolitis

BACKGROUND: Gut microbiota-derived short-chain fatty-acid (SFCA) acetate protects mice against RSV A2 strain infection by increasing interferon-β production and expression of interferon-stimulated genes (ISGs). However, the role of SFCA in RSV infection using strains isolated from patients is unknow...

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Detalles Bibliográficos
Autores principales: Antunes, Krist H., Stein, Renato T., Franceschina, Caroline, da Silva, Emanuelle F., de Freitas, Deise N., Silveira, Josiane, Mocellin, Magáli, Leitão, Lidiane, Fachi, José L., Pral, Laís P., Gonzalez, Amanda, Oliveira, Sarah, Duarte, Leonardo, Cassão, Gisele, Gonçalves, João I.B., Reis, Tatiane M., Abbadi, Bruno L, Dornelles, Maiele, Sperotto, Nathália D.M., Rigo, Maurício, Rodrigues, Hosana, Jones, Marcus, Epifanio, Matias, Guima, Suzana, Setubal, João C., Jorge, Taissa R., Mansur, Daniel S., Mayer, Fabiana Q., Varela, Ana Paula M., Bizarro, Cristiano V., Machado, Pablo, Basso, Luiz A., Polack, Fernando P., Custovic, Adnan, Vinolo, Marco A.R., de Souza, Ana Paula D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871125/
https://www.ncbi.nlm.nih.gov/pubmed/35220042
http://dx.doi.org/10.1016/j.ebiom.2022.103891

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