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Atypical Polypoid Adenomyoma of the Vagina: Follow Up and Subsequent Evolution: A Case Report and Update
Atypical polypoid adenomyoma (APA) is a rare tumor developed from a mix of cells of epithelial and mesenchymal origin. We present the case of an 84-year-old patient with atypical polypoid adenomyoma on the vaginal vault, after total hysterectomy with total adnexectomy for endometrial hyperplasia wit...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871313/ https://www.ncbi.nlm.nih.gov/pubmed/35204457 http://dx.doi.org/10.3390/diagnostics12020368 |
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author | Mitranovici, Melinda Ildiko Oală, Ioan Emilian Petre, Izabella Craina, Marius Lucian Floruț, Silviana Narcisa Chiorean, Diana Maria Cocuz, Iuliu Gabriel Turdean, Sabin Gligore Cotoi, Ovidiu Simion Pușcașiu, Lucian |
author_facet | Mitranovici, Melinda Ildiko Oală, Ioan Emilian Petre, Izabella Craina, Marius Lucian Floruț, Silviana Narcisa Chiorean, Diana Maria Cocuz, Iuliu Gabriel Turdean, Sabin Gligore Cotoi, Ovidiu Simion Pușcașiu, Lucian |
author_sort | Mitranovici, Melinda Ildiko |
collection | PubMed |
description | Atypical polypoid adenomyoma (APA) is a rare tumor developed from a mix of cells of epithelial and mesenchymal origin. We present the case of an 84-year-old patient with atypical polypoid adenomyoma on the vaginal vault, after total hysterectomy with total adnexectomy for endometrial hyperplasia with atypia four years ago. Not following regular indicated gynecological appointments, the symptoms presented were vaginal bleeding and anemia. The importance of the case consists both in the unique way in which the adenomyoma appears on the vaginal vault and in the subsequent evolution of this pathology. After complete resection, it recurs in five months with a malignant transformation into carcinosarcoma. This fact shows that adenomas can turn not only into carcinomas but also the mesenchymal component can progress to sarcoma, a fact of exceptional rarity. Follow-up and accurate diagnosis are essential for proper management, which is a challenge anyway due to the lack of case studies. |
format | Online Article Text |
id | pubmed-8871313 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-88713132022-02-25 Atypical Polypoid Adenomyoma of the Vagina: Follow Up and Subsequent Evolution: A Case Report and Update Mitranovici, Melinda Ildiko Oală, Ioan Emilian Petre, Izabella Craina, Marius Lucian Floruț, Silviana Narcisa Chiorean, Diana Maria Cocuz, Iuliu Gabriel Turdean, Sabin Gligore Cotoi, Ovidiu Simion Pușcașiu, Lucian Diagnostics (Basel) Case Report Atypical polypoid adenomyoma (APA) is a rare tumor developed from a mix of cells of epithelial and mesenchymal origin. We present the case of an 84-year-old patient with atypical polypoid adenomyoma on the vaginal vault, after total hysterectomy with total adnexectomy for endometrial hyperplasia with atypia four years ago. Not following regular indicated gynecological appointments, the symptoms presented were vaginal bleeding and anemia. The importance of the case consists both in the unique way in which the adenomyoma appears on the vaginal vault and in the subsequent evolution of this pathology. After complete resection, it recurs in five months with a malignant transformation into carcinosarcoma. This fact shows that adenomas can turn not only into carcinomas but also the mesenchymal component can progress to sarcoma, a fact of exceptional rarity. Follow-up and accurate diagnosis are essential for proper management, which is a challenge anyway due to the lack of case studies. MDPI 2022-02-01 /pmc/articles/PMC8871313/ /pubmed/35204457 http://dx.doi.org/10.3390/diagnostics12020368 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Mitranovici, Melinda Ildiko Oală, Ioan Emilian Petre, Izabella Craina, Marius Lucian Floruț, Silviana Narcisa Chiorean, Diana Maria Cocuz, Iuliu Gabriel Turdean, Sabin Gligore Cotoi, Ovidiu Simion Pușcașiu, Lucian Atypical Polypoid Adenomyoma of the Vagina: Follow Up and Subsequent Evolution: A Case Report and Update |
title | Atypical Polypoid Adenomyoma of the Vagina: Follow Up and Subsequent Evolution: A Case Report and Update |
title_full | Atypical Polypoid Adenomyoma of the Vagina: Follow Up and Subsequent Evolution: A Case Report and Update |
title_fullStr | Atypical Polypoid Adenomyoma of the Vagina: Follow Up and Subsequent Evolution: A Case Report and Update |
title_full_unstemmed | Atypical Polypoid Adenomyoma of the Vagina: Follow Up and Subsequent Evolution: A Case Report and Update |
title_short | Atypical Polypoid Adenomyoma of the Vagina: Follow Up and Subsequent Evolution: A Case Report and Update |
title_sort | atypical polypoid adenomyoma of the vagina: follow up and subsequent evolution: a case report and update |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871313/ https://www.ncbi.nlm.nih.gov/pubmed/35204457 http://dx.doi.org/10.3390/diagnostics12020368 |
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