Cargando…

Atypical Polypoid Adenomyoma of the Vagina: Follow Up and Subsequent Evolution: A Case Report and Update

Atypical polypoid adenomyoma (APA) is a rare tumor developed from a mix of cells of epithelial and mesenchymal origin. We present the case of an 84-year-old patient with atypical polypoid adenomyoma on the vaginal vault, after total hysterectomy with total adnexectomy for endometrial hyperplasia wit...

Descripción completa

Detalles Bibliográficos
Autores principales: Mitranovici, Melinda Ildiko, Oală, Ioan Emilian, Petre, Izabella, Craina, Marius Lucian, Floruț, Silviana Narcisa, Chiorean, Diana Maria, Cocuz, Iuliu Gabriel, Turdean, Sabin Gligore, Cotoi, Ovidiu Simion, Pușcașiu, Lucian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871313/
https://www.ncbi.nlm.nih.gov/pubmed/35204457
http://dx.doi.org/10.3390/diagnostics12020368
_version_ 1784656966925156352
author Mitranovici, Melinda Ildiko
Oală, Ioan Emilian
Petre, Izabella
Craina, Marius Lucian
Floruț, Silviana Narcisa
Chiorean, Diana Maria
Cocuz, Iuliu Gabriel
Turdean, Sabin Gligore
Cotoi, Ovidiu Simion
Pușcașiu, Lucian
author_facet Mitranovici, Melinda Ildiko
Oală, Ioan Emilian
Petre, Izabella
Craina, Marius Lucian
Floruț, Silviana Narcisa
Chiorean, Diana Maria
Cocuz, Iuliu Gabriel
Turdean, Sabin Gligore
Cotoi, Ovidiu Simion
Pușcașiu, Lucian
author_sort Mitranovici, Melinda Ildiko
collection PubMed
description Atypical polypoid adenomyoma (APA) is a rare tumor developed from a mix of cells of epithelial and mesenchymal origin. We present the case of an 84-year-old patient with atypical polypoid adenomyoma on the vaginal vault, after total hysterectomy with total adnexectomy for endometrial hyperplasia with atypia four years ago. Not following regular indicated gynecological appointments, the symptoms presented were vaginal bleeding and anemia. The importance of the case consists both in the unique way in which the adenomyoma appears on the vaginal vault and in the subsequent evolution of this pathology. After complete resection, it recurs in five months with a malignant transformation into carcinosarcoma. This fact shows that adenomas can turn not only into carcinomas but also the mesenchymal component can progress to sarcoma, a fact of exceptional rarity. Follow-up and accurate diagnosis are essential for proper management, which is a challenge anyway due to the lack of case studies.
format Online
Article
Text
id pubmed-8871313
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-88713132022-02-25 Atypical Polypoid Adenomyoma of the Vagina: Follow Up and Subsequent Evolution: A Case Report and Update Mitranovici, Melinda Ildiko Oală, Ioan Emilian Petre, Izabella Craina, Marius Lucian Floruț, Silviana Narcisa Chiorean, Diana Maria Cocuz, Iuliu Gabriel Turdean, Sabin Gligore Cotoi, Ovidiu Simion Pușcașiu, Lucian Diagnostics (Basel) Case Report Atypical polypoid adenomyoma (APA) is a rare tumor developed from a mix of cells of epithelial and mesenchymal origin. We present the case of an 84-year-old patient with atypical polypoid adenomyoma on the vaginal vault, after total hysterectomy with total adnexectomy for endometrial hyperplasia with atypia four years ago. Not following regular indicated gynecological appointments, the symptoms presented were vaginal bleeding and anemia. The importance of the case consists both in the unique way in which the adenomyoma appears on the vaginal vault and in the subsequent evolution of this pathology. After complete resection, it recurs in five months with a malignant transformation into carcinosarcoma. This fact shows that adenomas can turn not only into carcinomas but also the mesenchymal component can progress to sarcoma, a fact of exceptional rarity. Follow-up and accurate diagnosis are essential for proper management, which is a challenge anyway due to the lack of case studies. MDPI 2022-02-01 /pmc/articles/PMC8871313/ /pubmed/35204457 http://dx.doi.org/10.3390/diagnostics12020368 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Mitranovici, Melinda Ildiko
Oală, Ioan Emilian
Petre, Izabella
Craina, Marius Lucian
Floruț, Silviana Narcisa
Chiorean, Diana Maria
Cocuz, Iuliu Gabriel
Turdean, Sabin Gligore
Cotoi, Ovidiu Simion
Pușcașiu, Lucian
Atypical Polypoid Adenomyoma of the Vagina: Follow Up and Subsequent Evolution: A Case Report and Update
title Atypical Polypoid Adenomyoma of the Vagina: Follow Up and Subsequent Evolution: A Case Report and Update
title_full Atypical Polypoid Adenomyoma of the Vagina: Follow Up and Subsequent Evolution: A Case Report and Update
title_fullStr Atypical Polypoid Adenomyoma of the Vagina: Follow Up and Subsequent Evolution: A Case Report and Update
title_full_unstemmed Atypical Polypoid Adenomyoma of the Vagina: Follow Up and Subsequent Evolution: A Case Report and Update
title_short Atypical Polypoid Adenomyoma of the Vagina: Follow Up and Subsequent Evolution: A Case Report and Update
title_sort atypical polypoid adenomyoma of the vagina: follow up and subsequent evolution: a case report and update
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871313/
https://www.ncbi.nlm.nih.gov/pubmed/35204457
http://dx.doi.org/10.3390/diagnostics12020368
work_keys_str_mv AT mitranovicimelindaildiko atypicalpolypoidadenomyomaofthevaginafollowupandsubsequentevolutionacasereportandupdate
AT oalaioanemilian atypicalpolypoidadenomyomaofthevaginafollowupandsubsequentevolutionacasereportandupdate
AT petreizabella atypicalpolypoidadenomyomaofthevaginafollowupandsubsequentevolutionacasereportandupdate
AT crainamariuslucian atypicalpolypoidadenomyomaofthevaginafollowupandsubsequentevolutionacasereportandupdate
AT florutsilviananarcisa atypicalpolypoidadenomyomaofthevaginafollowupandsubsequentevolutionacasereportandupdate
AT chioreandianamaria atypicalpolypoidadenomyomaofthevaginafollowupandsubsequentevolutionacasereportandupdate
AT cocuziuliugabriel atypicalpolypoidadenomyomaofthevaginafollowupandsubsequentevolutionacasereportandupdate
AT turdeansabingligore atypicalpolypoidadenomyomaofthevaginafollowupandsubsequentevolutionacasereportandupdate
AT cotoiovidiusimion atypicalpolypoidadenomyomaofthevaginafollowupandsubsequentevolutionacasereportandupdate
AT puscasiulucian atypicalpolypoidadenomyomaofthevaginafollowupandsubsequentevolutionacasereportandupdate