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Breast Radiation Exposure of 3D Digital Breast Tomosynthesis Compared to Full-Field Digital Mammography in a Clinical Follow-Up Setting

According to a position paper of the European Commission Initiative on Breast Cancer (ECIBC), DBT is close to being introduced in European breast cancer screening programmes. Our study aimed to examine radiation dose delivered by digital breast tomosynthesis (DBT) and digital mammography (FFDM) in c...

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Autores principales: Opitz, Marcel, Zensen, Sebastian, Breuckmann, Katharina, Bos, Denise, Forsting, Michael, Hoffmann, Oliver, Stuschke, Martin, Wetter, Axel, Guberina, Nika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871344/
https://www.ncbi.nlm.nih.gov/pubmed/35204547
http://dx.doi.org/10.3390/diagnostics12020456
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author Opitz, Marcel
Zensen, Sebastian
Breuckmann, Katharina
Bos, Denise
Forsting, Michael
Hoffmann, Oliver
Stuschke, Martin
Wetter, Axel
Guberina, Nika
author_facet Opitz, Marcel
Zensen, Sebastian
Breuckmann, Katharina
Bos, Denise
Forsting, Michael
Hoffmann, Oliver
Stuschke, Martin
Wetter, Axel
Guberina, Nika
author_sort Opitz, Marcel
collection PubMed
description According to a position paper of the European Commission Initiative on Breast Cancer (ECIBC), DBT is close to being introduced in European breast cancer screening programmes. Our study aimed to examine radiation dose delivered by digital breast tomosynthesis (DBT) and digital mammography (FFDM) in comparison to sole FFDM in a clinical follow-up setting and in an identical patient cohort. Retrospectively, 768 breast examinations of 96 patients were included. Patients received both DBT and FFDM between May 2015 and July 2019: (I) FFDM in cranio-caudal (CC) and DBT in mediolateral oblique (MLO) view, as well as a (II) follow-up examination with FFDM in CC and MLO view. The mean glandular dose (MGD) was determined by the mammography system according to Dance’s model. The MGD (standard deviation (SD), interquartile range (IQR)) was distributed as follows: (I) (CC(FFDM)+MLO(DBT)) (a) left FFDM(CC) 1.40 mGy (0.36 mGy, 1.13–1.59 mGy), left DBT(MLO) 1.62 mGy (0.51 mGy, 1.27–1.82 mGy); (b) right FFDM(CC) 1.36 mGy (0.34 mGy, 1.14–1.51 mGy), right DBT(MLO) 1.59 mGy (0.52 mGy, 1.27–1.62 mGy). (II) (CC(FFDM)+MLO(FFDM)) (a) left FFDM(CC) 1.35 mGy (0.35 mGy, 1.10–1.60 mGy), left FFDM(MLO) 1.40 mGy (0.39 mGy, 1.12–1.59 mGy), (b) right FFDM(CC) 1.35 mGy (0.33 mGy, 1.12–1.48 mGy), right FFDM(MLO) 1.40 mGy (0.36 mGy, 1.14–1.58 mGy). MGD was significantly higher for DBT mlo views compared to FFDM (p < 0.001). Radiation dose was significantly higher for DBT in MLO views compared to FFDM. However, the MGD of DBT MLO lies below the national diagnostic reference level of 2 mGy for an FFDM view. Hence, our results support the use of either DBT or FFDM as suggested in the ECIBC’s Guidelines.
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spelling pubmed-88713442022-02-25 Breast Radiation Exposure of 3D Digital Breast Tomosynthesis Compared to Full-Field Digital Mammography in a Clinical Follow-Up Setting Opitz, Marcel Zensen, Sebastian Breuckmann, Katharina Bos, Denise Forsting, Michael Hoffmann, Oliver Stuschke, Martin Wetter, Axel Guberina, Nika Diagnostics (Basel) Article According to a position paper of the European Commission Initiative on Breast Cancer (ECIBC), DBT is close to being introduced in European breast cancer screening programmes. Our study aimed to examine radiation dose delivered by digital breast tomosynthesis (DBT) and digital mammography (FFDM) in comparison to sole FFDM in a clinical follow-up setting and in an identical patient cohort. Retrospectively, 768 breast examinations of 96 patients were included. Patients received both DBT and FFDM between May 2015 and July 2019: (I) FFDM in cranio-caudal (CC) and DBT in mediolateral oblique (MLO) view, as well as a (II) follow-up examination with FFDM in CC and MLO view. The mean glandular dose (MGD) was determined by the mammography system according to Dance’s model. The MGD (standard deviation (SD), interquartile range (IQR)) was distributed as follows: (I) (CC(FFDM)+MLO(DBT)) (a) left FFDM(CC) 1.40 mGy (0.36 mGy, 1.13–1.59 mGy), left DBT(MLO) 1.62 mGy (0.51 mGy, 1.27–1.82 mGy); (b) right FFDM(CC) 1.36 mGy (0.34 mGy, 1.14–1.51 mGy), right DBT(MLO) 1.59 mGy (0.52 mGy, 1.27–1.62 mGy). (II) (CC(FFDM)+MLO(FFDM)) (a) left FFDM(CC) 1.35 mGy (0.35 mGy, 1.10–1.60 mGy), left FFDM(MLO) 1.40 mGy (0.39 mGy, 1.12–1.59 mGy), (b) right FFDM(CC) 1.35 mGy (0.33 mGy, 1.12–1.48 mGy), right FFDM(MLO) 1.40 mGy (0.36 mGy, 1.14–1.58 mGy). MGD was significantly higher for DBT mlo views compared to FFDM (p < 0.001). Radiation dose was significantly higher for DBT in MLO views compared to FFDM. However, the MGD of DBT MLO lies below the national diagnostic reference level of 2 mGy for an FFDM view. Hence, our results support the use of either DBT or FFDM as suggested in the ECIBC’s Guidelines. MDPI 2022-02-10 /pmc/articles/PMC8871344/ /pubmed/35204547 http://dx.doi.org/10.3390/diagnostics12020456 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Opitz, Marcel
Zensen, Sebastian
Breuckmann, Katharina
Bos, Denise
Forsting, Michael
Hoffmann, Oliver
Stuschke, Martin
Wetter, Axel
Guberina, Nika
Breast Radiation Exposure of 3D Digital Breast Tomosynthesis Compared to Full-Field Digital Mammography in a Clinical Follow-Up Setting
title Breast Radiation Exposure of 3D Digital Breast Tomosynthesis Compared to Full-Field Digital Mammography in a Clinical Follow-Up Setting
title_full Breast Radiation Exposure of 3D Digital Breast Tomosynthesis Compared to Full-Field Digital Mammography in a Clinical Follow-Up Setting
title_fullStr Breast Radiation Exposure of 3D Digital Breast Tomosynthesis Compared to Full-Field Digital Mammography in a Clinical Follow-Up Setting
title_full_unstemmed Breast Radiation Exposure of 3D Digital Breast Tomosynthesis Compared to Full-Field Digital Mammography in a Clinical Follow-Up Setting
title_short Breast Radiation Exposure of 3D Digital Breast Tomosynthesis Compared to Full-Field Digital Mammography in a Clinical Follow-Up Setting
title_sort breast radiation exposure of 3d digital breast tomosynthesis compared to full-field digital mammography in a clinical follow-up setting
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871344/
https://www.ncbi.nlm.nih.gov/pubmed/35204547
http://dx.doi.org/10.3390/diagnostics12020456
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