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Undetected Omicron Transmission in Romania—Report of the First Detected Case of Locally Acquired Omicron Infection and Complete Epidemiological Investigation

The occurrence of the omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has importantly impacted surveillance and diagnosis, and has changed the therapeutic landscape of coronavirus disease 2019 (COVID-19). We present the first documented case of locally acquired SARS-C...

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Autores principales: Streinu-Cercel, Anca, Săndulescu, Oana, Miron, Victor Daniel, Paraschiv, Simona, Casangiu, Corina, Hohan, Robert, Bănică, Leontina, Surleac, Marius, Streinu-Cercel, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871416/
https://www.ncbi.nlm.nih.gov/pubmed/35204439
http://dx.doi.org/10.3390/diagnostics12020348
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author Streinu-Cercel, Anca
Săndulescu, Oana
Miron, Victor Daniel
Paraschiv, Simona
Casangiu, Corina
Hohan, Robert
Bănică, Leontina
Surleac, Marius
Streinu-Cercel, Adrian
author_facet Streinu-Cercel, Anca
Săndulescu, Oana
Miron, Victor Daniel
Paraschiv, Simona
Casangiu, Corina
Hohan, Robert
Bănică, Leontina
Surleac, Marius
Streinu-Cercel, Adrian
author_sort Streinu-Cercel, Anca
collection PubMed
description The occurrence of the omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has importantly impacted surveillance and diagnosis, and has changed the therapeutic landscape of coronavirus disease 2019 (COVID-19). We present the first documented case of locally acquired SARS-CoV-2 omicron variant in Romania in a patient with no recent travel outside the country. We also present the full results of the epidemiological investigation that led to the identification of the index case in a co-worker who had developed mild symptoms shortly after returning from the UK and who had undergone multiple rapid antigen tests with negative results prior to being tested by RT-PCR. We highlight potential lessons learned and describe further directions for actionable research and development in the field of COVID-19.
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spelling pubmed-88714162022-02-25 Undetected Omicron Transmission in Romania—Report of the First Detected Case of Locally Acquired Omicron Infection and Complete Epidemiological Investigation Streinu-Cercel, Anca Săndulescu, Oana Miron, Victor Daniel Paraschiv, Simona Casangiu, Corina Hohan, Robert Bănică, Leontina Surleac, Marius Streinu-Cercel, Adrian Diagnostics (Basel) Communication The occurrence of the omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has importantly impacted surveillance and diagnosis, and has changed the therapeutic landscape of coronavirus disease 2019 (COVID-19). We present the first documented case of locally acquired SARS-CoV-2 omicron variant in Romania in a patient with no recent travel outside the country. We also present the full results of the epidemiological investigation that led to the identification of the index case in a co-worker who had developed mild symptoms shortly after returning from the UK and who had undergone multiple rapid antigen tests with negative results prior to being tested by RT-PCR. We highlight potential lessons learned and describe further directions for actionable research and development in the field of COVID-19. MDPI 2022-01-29 /pmc/articles/PMC8871416/ /pubmed/35204439 http://dx.doi.org/10.3390/diagnostics12020348 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Streinu-Cercel, Anca
Săndulescu, Oana
Miron, Victor Daniel
Paraschiv, Simona
Casangiu, Corina
Hohan, Robert
Bănică, Leontina
Surleac, Marius
Streinu-Cercel, Adrian
Undetected Omicron Transmission in Romania—Report of the First Detected Case of Locally Acquired Omicron Infection and Complete Epidemiological Investigation
title Undetected Omicron Transmission in Romania—Report of the First Detected Case of Locally Acquired Omicron Infection and Complete Epidemiological Investigation
title_full Undetected Omicron Transmission in Romania—Report of the First Detected Case of Locally Acquired Omicron Infection and Complete Epidemiological Investigation
title_fullStr Undetected Omicron Transmission in Romania—Report of the First Detected Case of Locally Acquired Omicron Infection and Complete Epidemiological Investigation
title_full_unstemmed Undetected Omicron Transmission in Romania—Report of the First Detected Case of Locally Acquired Omicron Infection and Complete Epidemiological Investigation
title_short Undetected Omicron Transmission in Romania—Report of the First Detected Case of Locally Acquired Omicron Infection and Complete Epidemiological Investigation
title_sort undetected omicron transmission in romania—report of the first detected case of locally acquired omicron infection and complete epidemiological investigation
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871416/
https://www.ncbi.nlm.nih.gov/pubmed/35204439
http://dx.doi.org/10.3390/diagnostics12020348
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