Cargando…

Ginsenoside Rg2 alleviates myocardial fibrosis by regulating TGF-β1/Smad signalling pathway

CONTEXT: Panax ginseng C.A. Meyer (Araliaceae) has cardioprotective effects. Ginsenosides are responsible for most of the pharmacological activities of ginseng. OBJECTIVE: This study investigates the effect of ginsenoside Rg2 on myocardial fibrosis in myocardial ischaemia rats. MATERIALS AND METHODS...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Quanwei, Fu, Wenwen, Yu, Xiaofeng, Xu, Huali, Sui, Dayun, Wang, Yeling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871615/ https://www.ncbi.nlm.nih.gov/pubmed/33535854 http://dx.doi.org/10.1080/13880209.2020.1867197

Ejemplares similares

20(S)-Ginsenoside Rg2 attenuates myocardial ischemia/reperfusion injury by reducing oxidative stress and inflammation: role of SIRT1
por: Fu, Wenwen, et al.
Publicado: (2018)

Ginsenoside Rc attenuates myocardial ischaemic injury through antioxidative and anti-inflammatory effects
por: Shi, Lei, et al.
Publicado: (2022)

Ginsenoside Rg3 Alleviates ox-LDL Induced Endothelial Dysfunction and Prevents Atherosclerosis in ApoE(−/−) Mice by Regulating PPARγ/FAK Signaling Pathway
por: Geng, Jianan, et al.
Publicado: (2020)

Ginsenoside Rg3 induces ginsenoside Rb1-comparable cardioprotective effects independent of reducing blood pressure in spontaneously hypertensive rats
por: Jiang, Yichuan, et al.
Publicado: (2017)

Ginsenoside Rg1 Ameliorates Cigarette Smoke-Induced Airway Fibrosis by Suppressing the TGF-β1/Smad Pathway In Vivo and In Vitro
por: Guan, Sibin, et al.
Publicado: (2017)

Ginsenoside Rg3 has effects comparable to those of ginsenoside re on diabetic kidney disease prevention in db/db mice by regulating inflammation, fibrosis and PPARγ
por: Sui, Zhe, et al.
Publicado: (2023)

Combination of the ginsenosides Rb3 and Rb2 exerts protective effects against myocardial ischemia reperfusion injury in rats
por: Liu, Xiaomin, et al.
Publicado: (2020)

Ginsenoside Rc Ameliorates Endothelial Insulin Resistance via Upregulation of Angiotensin-Converting Enzyme 2
por: Wang, Yaozhen, et al.
Publicado: (2021)

Ginsenoside Rg3 Attenuates Angiotensin II-Mediated Renal Injury in Rats and Mice by Upregulating Angiotensin-Converting Enzyme 2 in the Renal Tissue
por: Liu, Hui, et al.
Publicado: (2019)

Ginsenoside Rg3 inhibits keloid fibroblast proliferation, angiogenesis and collagen synthesis in vitro via the TGF-β/Smad and ERK signaling pathways
por: Tang, Mengyao, et al.
Publicado: (2018)

Combination of Ginsenoside Rg1 and Astragaloside IV reduces oxidative stress and inhibits TGF-β1/Smads signaling cascade on renal fibrosis in rats with diabetic nephropathy
por: Du, Na, et al.
Publicado: (2018)

Ginsenoside Rg1 Attenuates Cigarette Smoke-Induced Pulmonary Epithelial-Mesenchymal Transition via Inhibition of the TGF-β1/Smad Pathway
por: Guan, Sibin, et al.
Publicado: (2017)

Ginsenoside Re Improves Inflammation and Fibrosis in Hepatic Tissue by Upregulating PPARγ Expression and Inhibiting Oxidative Stress in db/db Mice
por: Jiang, Yichuan, et al.
Publicado: (2021)

Ginsenoside Rg1 Epigenetically Modulates Smad7 Expression in Liver Fibrosis via MicroRNA-152
por: Zhang, Rongrong, et al.
Publicado: (2023)

Pirfenidone Alleviates Choroidal Neovascular Fibrosis through TGF-β/Smad Signaling Pathway
por: Gao, Chuang, et al.
Publicado: (2021)

Ginsenoside-Rb3 protects the myocardium from ischemia-reperfusion injury via the inhibition of apoptosis in rats
por: LIU, XIAOMIN, et al.
Publicado: (2014)

ADRB2 inhibition combined with antioxidant treatment alleviates lung fibrosis by attenuating TGFβ/SMAD signaling in lung fibroblasts
por: Wan, Ruyan, et al.
Publicado: (2023)

TGF-β/Smad signaling in renal fibrosis
por: Meng, Xiao-Ming, et al.
Publicado: (2015)

Follistatin Attenuates Myocardial Fibrosis in Diabetic Cardiomyopathy via the TGF-β–Smad3 Pathway
por: Wang, Yinhui, et al.
Publicado: (2021)

Pseudo-Ginsenoside Rh2 induces A549 cells apoptosis via the Ras/Raf/ERK/p53 pathway
por: Wang, Yuchen, et al.
Publicado: (2018)

Hydrogen sulfide alleviates hypothyroidism-induced myocardial fibrosis in rats through stimulating autophagy and inhibiting TGF-β1/Smad2 pathway
por: Song, Xiong, et al.
Publicado: (2023)

Rosuvastatin protects against endothelial cell apoptosis in vitro and alleviates atherosclerosis in ApoE(-/-) mice by suppressing endoplasmic reticulum stress
por: Geng, Jianan, et al.
Publicado: (2020)

Corni Fructus Alleviates UUO-Induced Renal Fibrosis via TGF-β/Smad Signaling
por: Lee, Jin A., et al.
Publicado: (2022)

Ginsenoside Rg1 treatment alleviates renal fibrosis by inhibiting the NOX4–MAPK pathway in T2DM mice
por: Ji, Pengmin, et al.
Publicado: (2023)

TGF-β/Smad Signaling Pathway in Tubulointerstitial Fibrosis
por: Yu, Xiao-Yong, et al.
Publicado: (2022)

Tangshen Formula Improves Diabetes-Associated Myocardial Fibrosis by Inhibiting TGF-β/Smads and Wnt/β-Catenin Pathways
por: Hu, Lin, et al.
Publicado: (2021)

Ginsenoside Rg1 Alleviates Podocyte EMT Passage by Regulating AKT/GSK3 β/β-Catenin Pathway by Restoring Autophagic Activity
por: Shi, Yimin, et al.
Publicado: (2020)

Comparative Pharmacokinetics of Ginsenoside Rg(3) and Ginsenoside Rh(2) after Oral Administration of Ginsenoside Rg(3) in Normal and Walker 256 Tumor-bearing Rats
por: Fan, He, et al.
Publicado: (2016)

Caveolin-1 Scaffolding Domain Peptides Alleviate Liver Fibrosis by Inhibiting TGF-β1/Smad Signaling in Mice
por: Lu, Jing, et al.
Publicado: (2018)

Ginsenoside Rg1 alleviates repeated alcohol exposure-induced psychomotor and cognitive deficits
por: Huang, Lu, et al.
Publicado: (2020)

Protective effect and mechanism of ginsenoside Rg2 on atherosclerosis
por: Xue, Qianqian, et al.
Publicado: (2023)

Ginsenoside Rg3 attenuates pulmonary fibrosis by inhibiting endothelial to mesenchymal transition
por: Yun, Eunsik, et al.
Publicado: (2023)

Ginsenoside Rg3 inhibits pulmonary fibrosis by preventing HIF-1α nuclear localisation
por: Fu, Zhuo, et al.
Publicado: (2021)

Mindin deficiency alleviates renal fibrosis through inhibiting NF‐κB and TGF‐β/Smad pathways
por: Yang, Kang, et al.
Publicado: (2020)

Diverse Roles of TGF-β/Smads in Renal Fibrosis and Inflammation
por: Lan, Hui Yao
Publicado: (2011)

Targeting TGF-β Mediated SMAD Signaling for the Prevention of Fibrosis
por: Walton, Kelly L., et al.
Publicado: (2017)

Panax quinquefolius L. Saponins Protect Myocardial Ischemia Reperfusion No-Reflow Through Inhibiting the Activation of NLRP3 Inflammasome via TLR4/MyD88/NF-κB Signaling Pathway
por: Yu, Ping, et al.
Publicado: (2021)

2-Arachidonoylglycerol Attenuates Myocardial Fibrosis in Diabetic Mice Via the TGF-β1/Smad Pathway
por: Chen, Zhengjie, et al.
Publicado: (2022)

Ginsenoside Rg1 Alleviates Acute Ulcerative Colitis by Modulating Gut Microbiota and Microbial Tryptophan Metabolism
por: Cheng, Hao, et al.
Publicado: (2022)

Ginsenoside Rg3 Improves Cardiac Function after Myocardial Ischemia/Reperfusion via Attenuating Apoptosis and Inflammation
por: Zhang, Li-ping, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_0um3m8k3majto9v8tgvt77fbci