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Alantolactone alleviates collagen-induced arthritis and inhibits Th17 cell differentiation through modulation of STAT3 signalling

CONTEXT: Alantolactone, the bioactive component in Inula helenium L. (Asteraceae), exhibits multiple biological effects. OBJECTIVE: We aimed to determine the anti-inflammatory effect of alantolactone in a collagen-induced arthritis (CIA) mouse model and its immunomodulatory effects on Th17 different...

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Detalles Bibliográficos
Autores principales: Chen, Hsiang-Lai, Lin, Shih Chao, Li, Shiming, Tang, Kuo-Tung, Lin, Chi-Chien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871681/
https://www.ncbi.nlm.nih.gov/pubmed/33556301
http://dx.doi.org/10.1080/13880209.2021.1876102

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