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Microglia Influence Neurofilament Deposition in ALS iPSC-Derived Motor Neurons

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease in which upper and lower motor neuron loss is the primary phenotype, leading to muscle weakness and wasting, respiratory failure, and death. Although a portion of ALS cases are linked to one of over 50 unique genes, the vast ma...

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Detalles Bibliográficos
Autores principales:	Allison, Reilly L., Adelman, Jacob W., Abrudan, Jenica, Urrutia, Raul A., Zimmermann, Michael T., Mathison, Angela J., Ebert, Allison D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871895/ https://www.ncbi.nlm.nih.gov/pubmed/35205286 http://dx.doi.org/10.3390/genes13020241

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