Cargando…

Organization of Post-Transplant Care and the 5-Year Outcomes of Kidney Transplantation

The outcomes of kidney transplantation depend on numerous factors and vary between transplant centers. The aim of this study is to assess the relationship between selected organizational factors, comorbidities, and patient and graft survival. This is a retrospective analysis of 438 renal transplant...

Descripción completa

Detalles Bibliográficos
Autores principales: Szymańska, Agnieszka, Mucha, Krzysztof, Kosieradzki, Maciej, Nazarewski, Sławomir, Pączek, Leszek, Foroncewicz, Bartosz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872049/
https://www.ncbi.nlm.nih.gov/pubmed/35206198
http://dx.doi.org/10.3390/ijerph19042010
_version_ 1784657141588557824
author Szymańska, Agnieszka
Mucha, Krzysztof
Kosieradzki, Maciej
Nazarewski, Sławomir
Pączek, Leszek
Foroncewicz, Bartosz
author_facet Szymańska, Agnieszka
Mucha, Krzysztof
Kosieradzki, Maciej
Nazarewski, Sławomir
Pączek, Leszek
Foroncewicz, Bartosz
author_sort Szymańska, Agnieszka
collection PubMed
description The outcomes of kidney transplantation depend on numerous factors and vary between transplant centers. The aim of this study is to assess the relationship between selected organizational factors, comorbidities, and patient and graft survival. This is a retrospective analysis of 438 renal transplant recipients (RTR) followed for 5 years. Patient and graft survival were evaluated in relation to hospitalization length, distance from the patient’s residence to the transplant center, the frequency of outpatient transplant visits, and the number and type of comorbidities. Five-year patient and graft survival rates were 93% and 90%, respectively. We found significant associations of patient survival with the prevalence of pre-transplant diabetes, cardiovascular diseases, malignancies, the number of comorbidities, and the first post-transplant hospitalization length. The incidence of infections, cardiovascular diseases, and transplanted kidney diseases was 60%, 40%, and 33%, respectively. As many as 41% of RTR had unknown etiology of primary kidney disease. In conclusion, the organization of post-transplant care needs to be adapted to the multi-morbidity of contemporary RTR and include multi-specialist care, especially in the context of current problems related to the COVID-19pandemic. The high proportion of patients with undetermined etiology of their primary renal disease carry the risk for additional complications during their long-term follow-up.
format Online
Article
Text
id pubmed-8872049
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-88720492022-02-25 Organization of Post-Transplant Care and the 5-Year Outcomes of Kidney Transplantation Szymańska, Agnieszka Mucha, Krzysztof Kosieradzki, Maciej Nazarewski, Sławomir Pączek, Leszek Foroncewicz, Bartosz Int J Environ Res Public Health Article The outcomes of kidney transplantation depend on numerous factors and vary between transplant centers. The aim of this study is to assess the relationship between selected organizational factors, comorbidities, and patient and graft survival. This is a retrospective analysis of 438 renal transplant recipients (RTR) followed for 5 years. Patient and graft survival were evaluated in relation to hospitalization length, distance from the patient’s residence to the transplant center, the frequency of outpatient transplant visits, and the number and type of comorbidities. Five-year patient and graft survival rates were 93% and 90%, respectively. We found significant associations of patient survival with the prevalence of pre-transplant diabetes, cardiovascular diseases, malignancies, the number of comorbidities, and the first post-transplant hospitalization length. The incidence of infections, cardiovascular diseases, and transplanted kidney diseases was 60%, 40%, and 33%, respectively. As many as 41% of RTR had unknown etiology of primary kidney disease. In conclusion, the organization of post-transplant care needs to be adapted to the multi-morbidity of contemporary RTR and include multi-specialist care, especially in the context of current problems related to the COVID-19pandemic. The high proportion of patients with undetermined etiology of their primary renal disease carry the risk for additional complications during their long-term follow-up. MDPI 2022-02-11 /pmc/articles/PMC8872049/ /pubmed/35206198 http://dx.doi.org/10.3390/ijerph19042010 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Szymańska, Agnieszka
Mucha, Krzysztof
Kosieradzki, Maciej
Nazarewski, Sławomir
Pączek, Leszek
Foroncewicz, Bartosz
Organization of Post-Transplant Care and the 5-Year Outcomes of Kidney Transplantation
title Organization of Post-Transplant Care and the 5-Year Outcomes of Kidney Transplantation
title_full Organization of Post-Transplant Care and the 5-Year Outcomes of Kidney Transplantation
title_fullStr Organization of Post-Transplant Care and the 5-Year Outcomes of Kidney Transplantation
title_full_unstemmed Organization of Post-Transplant Care and the 5-Year Outcomes of Kidney Transplantation
title_short Organization of Post-Transplant Care and the 5-Year Outcomes of Kidney Transplantation
title_sort organization of post-transplant care and the 5-year outcomes of kidney transplantation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872049/
https://www.ncbi.nlm.nih.gov/pubmed/35206198
http://dx.doi.org/10.3390/ijerph19042010
work_keys_str_mv AT szymanskaagnieszka organizationofposttransplantcareandthe5yearoutcomesofkidneytransplantation
AT muchakrzysztof organizationofposttransplantcareandthe5yearoutcomesofkidneytransplantation
AT kosieradzkimaciej organizationofposttransplantcareandthe5yearoutcomesofkidneytransplantation
AT nazarewskisławomir organizationofposttransplantcareandthe5yearoutcomesofkidneytransplantation
AT paczekleszek organizationofposttransplantcareandthe5yearoutcomesofkidneytransplantation
AT foroncewiczbartosz organizationofposttransplantcareandthe5yearoutcomesofkidneytransplantation