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Organization of Post-Transplant Care and the 5-Year Outcomes of Kidney Transplantation
The outcomes of kidney transplantation depend on numerous factors and vary between transplant centers. The aim of this study is to assess the relationship between selected organizational factors, comorbidities, and patient and graft survival. This is a retrospective analysis of 438 renal transplant...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872049/ https://www.ncbi.nlm.nih.gov/pubmed/35206198 http://dx.doi.org/10.3390/ijerph19042010 |
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author | Szymańska, Agnieszka Mucha, Krzysztof Kosieradzki, Maciej Nazarewski, Sławomir Pączek, Leszek Foroncewicz, Bartosz |
author_facet | Szymańska, Agnieszka Mucha, Krzysztof Kosieradzki, Maciej Nazarewski, Sławomir Pączek, Leszek Foroncewicz, Bartosz |
author_sort | Szymańska, Agnieszka |
collection | PubMed |
description | The outcomes of kidney transplantation depend on numerous factors and vary between transplant centers. The aim of this study is to assess the relationship between selected organizational factors, comorbidities, and patient and graft survival. This is a retrospective analysis of 438 renal transplant recipients (RTR) followed for 5 years. Patient and graft survival were evaluated in relation to hospitalization length, distance from the patient’s residence to the transplant center, the frequency of outpatient transplant visits, and the number and type of comorbidities. Five-year patient and graft survival rates were 93% and 90%, respectively. We found significant associations of patient survival with the prevalence of pre-transplant diabetes, cardiovascular diseases, malignancies, the number of comorbidities, and the first post-transplant hospitalization length. The incidence of infections, cardiovascular diseases, and transplanted kidney diseases was 60%, 40%, and 33%, respectively. As many as 41% of RTR had unknown etiology of primary kidney disease. In conclusion, the organization of post-transplant care needs to be adapted to the multi-morbidity of contemporary RTR and include multi-specialist care, especially in the context of current problems related to the COVID-19pandemic. The high proportion of patients with undetermined etiology of their primary renal disease carry the risk for additional complications during their long-term follow-up. |
format | Online Article Text |
id | pubmed-8872049 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-88720492022-02-25 Organization of Post-Transplant Care and the 5-Year Outcomes of Kidney Transplantation Szymańska, Agnieszka Mucha, Krzysztof Kosieradzki, Maciej Nazarewski, Sławomir Pączek, Leszek Foroncewicz, Bartosz Int J Environ Res Public Health Article The outcomes of kidney transplantation depend on numerous factors and vary between transplant centers. The aim of this study is to assess the relationship between selected organizational factors, comorbidities, and patient and graft survival. This is a retrospective analysis of 438 renal transplant recipients (RTR) followed for 5 years. Patient and graft survival were evaluated in relation to hospitalization length, distance from the patient’s residence to the transplant center, the frequency of outpatient transplant visits, and the number and type of comorbidities. Five-year patient and graft survival rates were 93% and 90%, respectively. We found significant associations of patient survival with the prevalence of pre-transplant diabetes, cardiovascular diseases, malignancies, the number of comorbidities, and the first post-transplant hospitalization length. The incidence of infections, cardiovascular diseases, and transplanted kidney diseases was 60%, 40%, and 33%, respectively. As many as 41% of RTR had unknown etiology of primary kidney disease. In conclusion, the organization of post-transplant care needs to be adapted to the multi-morbidity of contemporary RTR and include multi-specialist care, especially in the context of current problems related to the COVID-19pandemic. The high proportion of patients with undetermined etiology of their primary renal disease carry the risk for additional complications during their long-term follow-up. MDPI 2022-02-11 /pmc/articles/PMC8872049/ /pubmed/35206198 http://dx.doi.org/10.3390/ijerph19042010 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Szymańska, Agnieszka Mucha, Krzysztof Kosieradzki, Maciej Nazarewski, Sławomir Pączek, Leszek Foroncewicz, Bartosz Organization of Post-Transplant Care and the 5-Year Outcomes of Kidney Transplantation |
title | Organization of Post-Transplant Care and the 5-Year Outcomes of Kidney Transplantation |
title_full | Organization of Post-Transplant Care and the 5-Year Outcomes of Kidney Transplantation |
title_fullStr | Organization of Post-Transplant Care and the 5-Year Outcomes of Kidney Transplantation |
title_full_unstemmed | Organization of Post-Transplant Care and the 5-Year Outcomes of Kidney Transplantation |
title_short | Organization of Post-Transplant Care and the 5-Year Outcomes of Kidney Transplantation |
title_sort | organization of post-transplant care and the 5-year outcomes of kidney transplantation |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872049/ https://www.ncbi.nlm.nih.gov/pubmed/35206198 http://dx.doi.org/10.3390/ijerph19042010 |
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