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Seropositivity of SARS-CoV-2 in the Population of Kazakhstan: A Nationwide Laboratory-Based Surveillance

The data on seroprevalence of anti-SARS-CoV-2 antibodies in Kazakhstani population are non-existent, but are needed for planning of public health interventions targeted to COVID-19 containment. The aim of the study was to estimate the seropositivity of SARS-CoV-2 infection in the Kazakhstani populat...

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Autores principales: Semenova, Yuliya, Kalmatayeva, Zhanna, Oshibayeva, Ainash, Mamyrbekova, Saltanat, Kudirbekova, Aynura, Nurbakyt, Ardak, Baizhaxynova, Ardak, Colet, Paolo, Glushkova, Natalya, Ivankov, Alexandr, Sarria-Santamera, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872132/
https://www.ncbi.nlm.nih.gov/pubmed/35206453
http://dx.doi.org/10.3390/ijerph19042263
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author Semenova, Yuliya
Kalmatayeva, Zhanna
Oshibayeva, Ainash
Mamyrbekova, Saltanat
Kudirbekova, Aynura
Nurbakyt, Ardak
Baizhaxynova, Ardak
Colet, Paolo
Glushkova, Natalya
Ivankov, Alexandr
Sarria-Santamera, Antonio
author_facet Semenova, Yuliya
Kalmatayeva, Zhanna
Oshibayeva, Ainash
Mamyrbekova, Saltanat
Kudirbekova, Aynura
Nurbakyt, Ardak
Baizhaxynova, Ardak
Colet, Paolo
Glushkova, Natalya
Ivankov, Alexandr
Sarria-Santamera, Antonio
author_sort Semenova, Yuliya
collection PubMed
description The data on seroprevalence of anti-SARS-CoV-2 antibodies in Kazakhstani population are non-existent, but are needed for planning of public health interventions targeted to COVID-19 containment. The aim of the study was to estimate the seropositivity of SARS-CoV-2 infection in the Kazakhstani population from 2020 to 2021. We relied on the data obtained from the results from “IN VITRO” laboratories of enzyme-linked immunosorbent assays for class G immunoglobulins (IgG) and class M (IgM) to SARS-CoV-2. The association of COVID-19 seropositivity was assessed in relation to age, gender, and region of residence. Additionally, we related the monitoring of longitudinal seropositivity with COVID-19 statistics obtained from Our World in Data. The total numbers of tests were 68,732 for SARS-CoV-2 IgM and 85,346 for IgG, of which 22% and 63% were positive, respectively. The highest rates of positive anti-SARS-CoV-2 IgM results were seen during July/August 2020. The rate of IgM seropositivity was the lowest on 25 October 2020 (2%). The lowest daily rate of anti-SARS-CoV-2 IgG was 17% (13 December 2020), while the peak of IgG seropositivity was seen on 6 June 2021 (84%). A longitudinal serological study should be envisaged to facilitate understanding of the dynamics of the epidemiological situation and to forecast future scenarios.
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spelling pubmed-88721322022-02-25 Seropositivity of SARS-CoV-2 in the Population of Kazakhstan: A Nationwide Laboratory-Based Surveillance Semenova, Yuliya Kalmatayeva, Zhanna Oshibayeva, Ainash Mamyrbekova, Saltanat Kudirbekova, Aynura Nurbakyt, Ardak Baizhaxynova, Ardak Colet, Paolo Glushkova, Natalya Ivankov, Alexandr Sarria-Santamera, Antonio Int J Environ Res Public Health Article The data on seroprevalence of anti-SARS-CoV-2 antibodies in Kazakhstani population are non-existent, but are needed for planning of public health interventions targeted to COVID-19 containment. The aim of the study was to estimate the seropositivity of SARS-CoV-2 infection in the Kazakhstani population from 2020 to 2021. We relied on the data obtained from the results from “IN VITRO” laboratories of enzyme-linked immunosorbent assays for class G immunoglobulins (IgG) and class M (IgM) to SARS-CoV-2. The association of COVID-19 seropositivity was assessed in relation to age, gender, and region of residence. Additionally, we related the monitoring of longitudinal seropositivity with COVID-19 statistics obtained from Our World in Data. The total numbers of tests were 68,732 for SARS-CoV-2 IgM and 85,346 for IgG, of which 22% and 63% were positive, respectively. The highest rates of positive anti-SARS-CoV-2 IgM results were seen during July/August 2020. The rate of IgM seropositivity was the lowest on 25 October 2020 (2%). The lowest daily rate of anti-SARS-CoV-2 IgG was 17% (13 December 2020), while the peak of IgG seropositivity was seen on 6 June 2021 (84%). A longitudinal serological study should be envisaged to facilitate understanding of the dynamics of the epidemiological situation and to forecast future scenarios. MDPI 2022-02-17 /pmc/articles/PMC8872132/ /pubmed/35206453 http://dx.doi.org/10.3390/ijerph19042263 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Semenova, Yuliya
Kalmatayeva, Zhanna
Oshibayeva, Ainash
Mamyrbekova, Saltanat
Kudirbekova, Aynura
Nurbakyt, Ardak
Baizhaxynova, Ardak
Colet, Paolo
Glushkova, Natalya
Ivankov, Alexandr
Sarria-Santamera, Antonio
Seropositivity of SARS-CoV-2 in the Population of Kazakhstan: A Nationwide Laboratory-Based Surveillance
title Seropositivity of SARS-CoV-2 in the Population of Kazakhstan: A Nationwide Laboratory-Based Surveillance
title_full Seropositivity of SARS-CoV-2 in the Population of Kazakhstan: A Nationwide Laboratory-Based Surveillance
title_fullStr Seropositivity of SARS-CoV-2 in the Population of Kazakhstan: A Nationwide Laboratory-Based Surveillance
title_full_unstemmed Seropositivity of SARS-CoV-2 in the Population of Kazakhstan: A Nationwide Laboratory-Based Surveillance
title_short Seropositivity of SARS-CoV-2 in the Population of Kazakhstan: A Nationwide Laboratory-Based Surveillance
title_sort seropositivity of sars-cov-2 in the population of kazakhstan: a nationwide laboratory-based surveillance
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872132/
https://www.ncbi.nlm.nih.gov/pubmed/35206453
http://dx.doi.org/10.3390/ijerph19042263
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