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Novel Hydrogel Material with Tailored Internal Architecture Modified by “Bio” Amphiphilic Components—Design and Analysis by a Physico-Chemical Approach

Nowadays, hydrogels are found in many applications ranging from the industrial to the biological (e.g., tissue engineering, drug delivery systems, cosmetics, water treatment, and many more). According to the specific needs of individual applications, it is necessary to be able to modify the properti...

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Autores principales: Heger, Richard, Kadlec, Martin, Trudicova, Monika, Zinkovska, Natalia, Hajzler, Jan, Pekar, Miloslav, Smilek, Jiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872166/
https://www.ncbi.nlm.nih.gov/pubmed/35200496
http://dx.doi.org/10.3390/gels8020115
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author Heger, Richard
Kadlec, Martin
Trudicova, Monika
Zinkovska, Natalia
Hajzler, Jan
Pekar, Miloslav
Smilek, Jiri
author_facet Heger, Richard
Kadlec, Martin
Trudicova, Monika
Zinkovska, Natalia
Hajzler, Jan
Pekar, Miloslav
Smilek, Jiri
author_sort Heger, Richard
collection PubMed
description Nowadays, hydrogels are found in many applications ranging from the industrial to the biological (e.g., tissue engineering, drug delivery systems, cosmetics, water treatment, and many more). According to the specific needs of individual applications, it is necessary to be able to modify the properties of hydrogel materials, particularly the transport and mechanical properties related to their structure, which are crucial for the potential use of the hydrogels in modern material engineering. Therefore, the possibility of preparing hydrogel materials with tunable properties is a very real topic and is still being researched. A simple way to modify these properties is to alter the internal structure by adding another component. The addition of natural substances is convenient due to their biocompatibility and the possibility of biodegradation. Therefore, this work focused on hydrogels modified by a substance that is naturally found in the tissues of our body, namely lecithin. Hydrogels were prepared by different types of crosslinking (physical, ionic, and chemical). Their mechanical properties were monitored and these investigations were supplemented by drying and rehydration measurements, and supported by the morphological characterization of xerogels. With the addition of natural lecithin, it is possible to modify crucial properties of hydrogels such as porosity and mechanical properties, which will play a role in the final applications.
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spelling pubmed-88721662022-02-25 Novel Hydrogel Material with Tailored Internal Architecture Modified by “Bio” Amphiphilic Components—Design and Analysis by a Physico-Chemical Approach Heger, Richard Kadlec, Martin Trudicova, Monika Zinkovska, Natalia Hajzler, Jan Pekar, Miloslav Smilek, Jiri Gels Article Nowadays, hydrogels are found in many applications ranging from the industrial to the biological (e.g., tissue engineering, drug delivery systems, cosmetics, water treatment, and many more). According to the specific needs of individual applications, it is necessary to be able to modify the properties of hydrogel materials, particularly the transport and mechanical properties related to their structure, which are crucial for the potential use of the hydrogels in modern material engineering. Therefore, the possibility of preparing hydrogel materials with tunable properties is a very real topic and is still being researched. A simple way to modify these properties is to alter the internal structure by adding another component. The addition of natural substances is convenient due to their biocompatibility and the possibility of biodegradation. Therefore, this work focused on hydrogels modified by a substance that is naturally found in the tissues of our body, namely lecithin. Hydrogels were prepared by different types of crosslinking (physical, ionic, and chemical). Their mechanical properties were monitored and these investigations were supplemented by drying and rehydration measurements, and supported by the morphological characterization of xerogels. With the addition of natural lecithin, it is possible to modify crucial properties of hydrogels such as porosity and mechanical properties, which will play a role in the final applications. MDPI 2022-02-13 /pmc/articles/PMC8872166/ /pubmed/35200496 http://dx.doi.org/10.3390/gels8020115 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Heger, Richard
Kadlec, Martin
Trudicova, Monika
Zinkovska, Natalia
Hajzler, Jan
Pekar, Miloslav
Smilek, Jiri
Novel Hydrogel Material with Tailored Internal Architecture Modified by “Bio” Amphiphilic Components—Design and Analysis by a Physico-Chemical Approach
title Novel Hydrogel Material with Tailored Internal Architecture Modified by “Bio” Amphiphilic Components—Design and Analysis by a Physico-Chemical Approach
title_full Novel Hydrogel Material with Tailored Internal Architecture Modified by “Bio” Amphiphilic Components—Design and Analysis by a Physico-Chemical Approach
title_fullStr Novel Hydrogel Material with Tailored Internal Architecture Modified by “Bio” Amphiphilic Components—Design and Analysis by a Physico-Chemical Approach
title_full_unstemmed Novel Hydrogel Material with Tailored Internal Architecture Modified by “Bio” Amphiphilic Components—Design and Analysis by a Physico-Chemical Approach
title_short Novel Hydrogel Material with Tailored Internal Architecture Modified by “Bio” Amphiphilic Components—Design and Analysis by a Physico-Chemical Approach
title_sort novel hydrogel material with tailored internal architecture modified by “bio” amphiphilic components—design and analysis by a physico-chemical approach
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872166/
https://www.ncbi.nlm.nih.gov/pubmed/35200496
http://dx.doi.org/10.3390/gels8020115
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