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Increased Urinary Cadmium Levels in Foreign-Born Asian Women—An NHANES Study of 9639 U.S. Participants

The purpose of this study was to determine the disparities and trends in demographics, social behaviors, and occupations for cadmium exposure in the U.S. Data were obtained from the NHANES database from 2007 to 2016. Analysis of variance tests were used to compare the association of the geometric me...

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Autores principales: Milki, Anthony, Wong, Deanna, Chan, Chloe, Sooklal, Sarita, Kapp, Daniel S., Mann, Amandeep K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872212/
https://www.ncbi.nlm.nih.gov/pubmed/35206357
http://dx.doi.org/10.3390/ijerph19042170
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author Milki, Anthony
Wong, Deanna
Chan, Chloe
Sooklal, Sarita
Kapp, Daniel S.
Mann, Amandeep K.
author_facet Milki, Anthony
Wong, Deanna
Chan, Chloe
Sooklal, Sarita
Kapp, Daniel S.
Mann, Amandeep K.
author_sort Milki, Anthony
collection PubMed
description The purpose of this study was to determine the disparities and trends in demographics, social behaviors, and occupations for cadmium exposure in the U.S. Data were obtained from the NHANES database from 2007 to 2016. Analysis of variance tests were used to compare the association of the geometric mean values of urinary cadmium levels and various demographic and behavioral characteristics. We also conducted multivariable logistic regression while adjusting for these factors to determine the risk of toxic urinary cadmium levels (≥2 µg/g) across various patient characteristics. Of the 9639 participants, 52.8% were ≥45 years old, 51.7% female, and 48.3% male. White, Black, Mexican American, other Hispanic, and Asian comprised 66.4%, 11.5%, 8.7%, 5.8%, and 5.5%, respectively. Over 82% of participants were U.S. born. A total of 19.6% were current smokers. On multivariate analysis, older age (OR: 8.87), current smoking (OR = 5.74), Asian race (OR = 4.52), female sex (OR = 4.32), and foreign nativity (OR = 1.83) were significantly associated with higher cadmium levels. Older, Asian, foreign-born females showed a measurement of 0.69 μg/g, a value more than three-fold the sample population’s mean of 0.20 μg/g. A trend analysis demonstrated a cadmium level decrease over time (OR = 0.47). Asians had the highest urinary cadmium levels, especially older, foreign-born females. Smoking and poverty were also associated with significant elevations in cadmium levels.
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spelling pubmed-88722122022-02-25 Increased Urinary Cadmium Levels in Foreign-Born Asian Women—An NHANES Study of 9639 U.S. Participants Milki, Anthony Wong, Deanna Chan, Chloe Sooklal, Sarita Kapp, Daniel S. Mann, Amandeep K. Int J Environ Res Public Health Article The purpose of this study was to determine the disparities and trends in demographics, social behaviors, and occupations for cadmium exposure in the U.S. Data were obtained from the NHANES database from 2007 to 2016. Analysis of variance tests were used to compare the association of the geometric mean values of urinary cadmium levels and various demographic and behavioral characteristics. We also conducted multivariable logistic regression while adjusting for these factors to determine the risk of toxic urinary cadmium levels (≥2 µg/g) across various patient characteristics. Of the 9639 participants, 52.8% were ≥45 years old, 51.7% female, and 48.3% male. White, Black, Mexican American, other Hispanic, and Asian comprised 66.4%, 11.5%, 8.7%, 5.8%, and 5.5%, respectively. Over 82% of participants were U.S. born. A total of 19.6% were current smokers. On multivariate analysis, older age (OR: 8.87), current smoking (OR = 5.74), Asian race (OR = 4.52), female sex (OR = 4.32), and foreign nativity (OR = 1.83) were significantly associated with higher cadmium levels. Older, Asian, foreign-born females showed a measurement of 0.69 μg/g, a value more than three-fold the sample population’s mean of 0.20 μg/g. A trend analysis demonstrated a cadmium level decrease over time (OR = 0.47). Asians had the highest urinary cadmium levels, especially older, foreign-born females. Smoking and poverty were also associated with significant elevations in cadmium levels. MDPI 2022-02-15 /pmc/articles/PMC8872212/ /pubmed/35206357 http://dx.doi.org/10.3390/ijerph19042170 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Milki, Anthony
Wong, Deanna
Chan, Chloe
Sooklal, Sarita
Kapp, Daniel S.
Mann, Amandeep K.
Increased Urinary Cadmium Levels in Foreign-Born Asian Women—An NHANES Study of 9639 U.S. Participants
title Increased Urinary Cadmium Levels in Foreign-Born Asian Women—An NHANES Study of 9639 U.S. Participants
title_full Increased Urinary Cadmium Levels in Foreign-Born Asian Women—An NHANES Study of 9639 U.S. Participants
title_fullStr Increased Urinary Cadmium Levels in Foreign-Born Asian Women—An NHANES Study of 9639 U.S. Participants
title_full_unstemmed Increased Urinary Cadmium Levels in Foreign-Born Asian Women—An NHANES Study of 9639 U.S. Participants
title_short Increased Urinary Cadmium Levels in Foreign-Born Asian Women—An NHANES Study of 9639 U.S. Participants
title_sort increased urinary cadmium levels in foreign-born asian women—an nhanes study of 9639 u.s. participants
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872212/
https://www.ncbi.nlm.nih.gov/pubmed/35206357
http://dx.doi.org/10.3390/ijerph19042170
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