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The Association of Persistent Symptoms of Depression and Anxiety with Recurrent Acute Coronary Syndrome Events: A Prospective Observational Study

The purpose of this study was to examine the role of persistent symptoms of depression and anxiety in a second acute coronary syndrome (ACS) event. Data presented in this study were from an RCT study. A follow-up for 24 months after baseline to detect a second ACS event among 1162 patients from five...

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Autores principales: Alhurani, Abdullah S., Hamdan-Mansour, Ayman M., Ahmad, Muayyad M., McKee, Gabrielle, O’Donnell, Sharon, O’Brien, Frances, Mooney, Mary, Saleh, Zyad T., Moser, Debra K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872236/
https://www.ncbi.nlm.nih.gov/pubmed/35206994
http://dx.doi.org/10.3390/healthcare10020383
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author Alhurani, Abdullah S.
Hamdan-Mansour, Ayman M.
Ahmad, Muayyad M.
McKee, Gabrielle
O’Donnell, Sharon
O’Brien, Frances
Mooney, Mary
Saleh, Zyad T.
Moser, Debra K.
author_facet Alhurani, Abdullah S.
Hamdan-Mansour, Ayman M.
Ahmad, Muayyad M.
McKee, Gabrielle
O’Donnell, Sharon
O’Brien, Frances
Mooney, Mary
Saleh, Zyad T.
Moser, Debra K.
author_sort Alhurani, Abdullah S.
collection PubMed
description The purpose of this study was to examine the role of persistent symptoms of depression and anxiety in a second acute coronary syndrome (ACS) event. Data presented in this study were from an RCT study. A follow-up for 24 months after baseline to detect a second ACS event among 1162 patients from five hospitals. Hierarchal Cox regression analyses were used. The results showed that persistent depression only (HR 2.27; 95% CI: 1.35–3.81; p = 0.002), and comorbid persistent depression and anxiety (HR 2.03; 95% CI: 1.03–3.98; p = 0.040) were the significant predictors of a second ACS event. Secondary education level compared to primary educational level (HR 0.63; 95% CI: 0.43–0.93; p = 0.020) and college or more education level compared to primary educational level (HR 0.47; 95% CI: 0.27–0.84; p = 0.011) were the only demographic variables that were significant predictors of a second event. The study reveals that attention must be paid by healthcare providers to assess and manage persistent depression; particularly when it is co-morbid with anxiety.
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spelling pubmed-88722362022-02-25 The Association of Persistent Symptoms of Depression and Anxiety with Recurrent Acute Coronary Syndrome Events: A Prospective Observational Study Alhurani, Abdullah S. Hamdan-Mansour, Ayman M. Ahmad, Muayyad M. McKee, Gabrielle O’Donnell, Sharon O’Brien, Frances Mooney, Mary Saleh, Zyad T. Moser, Debra K. Healthcare (Basel) Article The purpose of this study was to examine the role of persistent symptoms of depression and anxiety in a second acute coronary syndrome (ACS) event. Data presented in this study were from an RCT study. A follow-up for 24 months after baseline to detect a second ACS event among 1162 patients from five hospitals. Hierarchal Cox regression analyses were used. The results showed that persistent depression only (HR 2.27; 95% CI: 1.35–3.81; p = 0.002), and comorbid persistent depression and anxiety (HR 2.03; 95% CI: 1.03–3.98; p = 0.040) were the significant predictors of a second ACS event. Secondary education level compared to primary educational level (HR 0.63; 95% CI: 0.43–0.93; p = 0.020) and college or more education level compared to primary educational level (HR 0.47; 95% CI: 0.27–0.84; p = 0.011) were the only demographic variables that were significant predictors of a second event. The study reveals that attention must be paid by healthcare providers to assess and manage persistent depression; particularly when it is co-morbid with anxiety. MDPI 2022-02-17 /pmc/articles/PMC8872236/ /pubmed/35206994 http://dx.doi.org/10.3390/healthcare10020383 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Alhurani, Abdullah S.
Hamdan-Mansour, Ayman M.
Ahmad, Muayyad M.
McKee, Gabrielle
O’Donnell, Sharon
O’Brien, Frances
Mooney, Mary
Saleh, Zyad T.
Moser, Debra K.
The Association of Persistent Symptoms of Depression and Anxiety with Recurrent Acute Coronary Syndrome Events: A Prospective Observational Study
title The Association of Persistent Symptoms of Depression and Anxiety with Recurrent Acute Coronary Syndrome Events: A Prospective Observational Study
title_full The Association of Persistent Symptoms of Depression and Anxiety with Recurrent Acute Coronary Syndrome Events: A Prospective Observational Study
title_fullStr The Association of Persistent Symptoms of Depression and Anxiety with Recurrent Acute Coronary Syndrome Events: A Prospective Observational Study
title_full_unstemmed The Association of Persistent Symptoms of Depression and Anxiety with Recurrent Acute Coronary Syndrome Events: A Prospective Observational Study
title_short The Association of Persistent Symptoms of Depression and Anxiety with Recurrent Acute Coronary Syndrome Events: A Prospective Observational Study
title_sort association of persistent symptoms of depression and anxiety with recurrent acute coronary syndrome events: a prospective observational study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872236/
https://www.ncbi.nlm.nih.gov/pubmed/35206994
http://dx.doi.org/10.3390/healthcare10020383
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