Cargando…

The Effects of FGF4 Retrogenes on Canine Morphology

Two FGF4 retrogenes (FGF4L1 on chromosome 18 and FGF4L2 on chromosome 12) have been identified to cause dwarfism across many dog breeds. Some breeds are nearly homozygous for both retrogenes (e.g., Dachshunds) and others are homozygous for just one (e.g., Beagles and Scottish Terriers). Since most b...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bannasch, Danika, Batcher, Kevin, Leuthard, Fabienne, Bannasch, Michael, Hug, Petra, Marcellin-Little, Denis J., Dickinson, Peter J., Drögemüller, Michaela, Drögemüller, Cord, Leeb, Tosso
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872533/ https://www.ncbi.nlm.nih.gov/pubmed/35205370 http://dx.doi.org/10.3390/genes13020325

Ejemplares similares

Phenotypic Effects of FGF4 Retrogenes on Intervertebral Disc Disease in Dogs
por: Batcher, Kevin, et al.
Publicado: (2019)

Multiple FGF4 Retrocopies Recently Derived within Canids
por: Batcher, Kevin, et al.
Publicado: (2020)

Ancient segmentally duplicated LCORL retrocopies in equids
por: Batcher, Kevin, et al.
Publicado: (2023)

FGF4 retrogene on CFA12 is responsible for chondrodystrophy and intervertebral disc disease in dogs
por: Brown, Emily A., et al.
Publicado: (2017)

ATP2A2 SINE Insertion in an Irish Terrier with Darier Disease and Associated Infundibular Cyst Formation
por: Linek, Monika, et al.
Publicado: (2020)

X-Linked Hypohidrotic Ectodermal Dysplasia in Crossbred Beef Cattle Due to a Large Deletion in EDA
por: O’Toole, Donal, et al.
Publicado: (2021)

X-linked anhidrotic ectodermal dysplasia (ED1) in men, mice, and cattle
por: Drögemüller, Cord, et al.
Publicado: (2003)

Dog colour patterns explained by modular promoters of ancient canid origin
por: Bannasch, Danika L., et al.
Publicado: (2021)

Whole Genome Sequencing Indicates Heterogeneity of Hyperostotic Disorders in Dogs
por: Letko, Anna, et al.
Publicado: (2020)

NME5 frameshift variant in Alaskan Malamutes with primary ciliary dyskinesia
por: Anderegg, Linda, et al.
Publicado: (2019)

Naturally occurring canine laminopathy leading to a dilated and fibrosing cardiomyopathy in the Nova Scotia Duck Tolling Retriever
por: Bannasch, Danika L., et al.
Publicado: (2023)

A 4 Mb High Resolution BAC Contig on Bovine Chromosome 1q12 and Comparative Analysis With Human Chromosome 21q22
por: Drögemüller, Cord, et al.
Publicado: (2005)

A Nonsense Variant in COL6A1 in Landseer Dogs with Muscular Dystrophy
por: Steffen, Frank, et al.
Publicado: (2015)

The effect of inbreeding, body size and morphology on health in dog breeds
por: Bannasch, Danika, et al.
Publicado: (2021)

A Missense Mutation in the Vacuolar Protein Sorting 11 (VPS11) Gene Is Associated with Neuroaxonal Dystrophy in Rottweiler Dogs
por: Lucot, Katherine L., et al.
Publicado: (2018)

SLC25A12 Missense Variant in Nova Scotia Duck Tolling Retrievers Affected by Cerebellar Degeneration—Myositis Complex (CDMC)
por: Christen, Matthias, et al.
Publicado: (2022)

An SNN retrocopy insertion upstream of GPR22 is associated with dark red coat color in Poodles
por: Batcher, Kevin, et al.
Publicado: (2022)

A Deletion in the VLDLR Gene in Eurasier Dogs with Cerebellar Hypoplasia Resembling a Dandy-Walker-Like Malformation (DWLM)
por: Gerber, Martina, et al.
Publicado: (2015)

Recent, full-length gene retrocopies are common in canids
por: Batcher, Kevin, et al.
Publicado: (2022)

Current Understanding of the Genetics of Intervertebral Disc Degeneration
por: Dickinson, Peter J., et al.
Publicado: (2020)

The LCORL Locus Is under Selection in Large-Sized Pakistani Goat Breeds
por: Saif, Rashid, et al.
Publicado: (2020)

A Locus on Chromosome 5 Is Associated with Dilated Cardiomyopathy in Doberman Pinschers
por: Mausberg, Theresa-Bernadette, et al.
Publicado: (2011)

A Missense Variant Affecting the C-Terminal Tail of UNC93B1 in Dogs with Exfoliative Cutaneous Lupus Erythematosus (ECLE)
por: Leeb, Tosso, et al.
Publicado: (2020)

A Mutation in the FAM83G Gene in Dogs with Hereditary Footpad Hyperkeratosis (HFH)
por: Drögemüller, Michaela, et al.
Publicado: (2014)

Novel Brown Coat Color (Cocoa) in French Bulldogs Results from a Nonsense Variant in HPS3
por: Kiener, Sarah, et al.
Publicado: (2020)

Characterization of the canine CLCN3 gene and evaluation as candidate for late-onset NCL
por: Wohlke, Anne, et al.
Publicado: (2006)

Identification of the Bovine Arachnomelia Mutation by Massively Parallel Sequencing Implicates Sulfite Oxidase (SUOX) in Bone Development
por: Drögemüller, Cord, et al.
Publicado: (2010)

Runs of homozygosity in Swiss goats reveal genetic changes associated with domestication and modern selection
por: Signer-Hasler, Heidi, et al.
Publicado: (2022)

A high resolution physical and RH map of pig chromosome 6q1.2 and comparative analysis with human chromosome 19q13.1
por: Martins-Wess, Flávia, et al.
Publicado: (2003)

A Frameshift Mutation in the Cubilin Gene (CUBN) in Border Collies with Imerslund-Gräsbeck Syndrome (Selective Cobalamin Malabsorption)
por: Owczarek-Lipska, Marta, et al.
Publicado: (2013)

Imputation of sequence level genotypes in the Franches-Montagnes horse breed
por: Frischknecht, Mirjam, et al.
Publicado: (2014)

Genomic amplification of the caprine EDNRA locus might lead to a dose dependent loss of pigmentation
por: Menzi, Fiona, et al.
Publicado: (2016)

PKD1 Nonsense Variant in a Lagotto Romagnolo Family with Polycystic Kidney Disease
por: Drögemüller, Michaela, et al.
Publicado: (2023)

Short and sweet: foreleg abnormalities in Havanese and the role of the FGF4 retrogene
por: Bellamy, Kim K. L., et al.
Publicado: (2020)

RetrogeneDB—A Database of Animal Retrogenes
por: Kabza, Michał, et al.
Publicado: (2014)

Dog as a Model for Osteoarthritis: The FGF4 Retrogene Insertion May Matter
por: Tellegen, Anna R., et al.
Publicado: (2019)

Congenital syndactyly in cattle: four novel mutations in the low density lipoprotein receptor-related protein 4 gene (LRP4)
por: Drögemüller, Cord, et al.
Publicado: (2007)

Burst of Young Retrogenes and Independent Retrogene Formation in Mammals
por: Pan, Deng, et al.
Publicado: (2009)

Localization of Canine Brachycephaly Using an Across Breed Mapping Approach
por: Bannasch, Danika, et al.
Publicado: (2010)

A Missense Variant in ALDH5A1 Associated with Canine Succinic Semialdehyde Dehydrogenase Deficiency (SSADHD) in the Saluki Dog
por: Vernau, Karen M., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_n4btumd95rbv569ama55r4a8ng