Cargando…

COVID-19 mRNA Vaccination Mimicking Heart Attack in a Healthy 56-Year-Old Physician

We report our experience regarding a 56-year-old physician who developed severe symptoms mimicking a heart attack a few days after receiving the second dose of the new mRNA vaccine of Pfizer-BioNTech for COVID-19 protection. The patient is a healthy individual with no comorbidities and a normal clin...

Descripción completa

Detalles Bibliográficos
Autores principales: Xinias, Ioannis, Mavroudi, Antigoni, Theodorou, Georgios-Theofilos, Roilidis, Ioannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872543/
https://www.ncbi.nlm.nih.gov/pubmed/35200439
http://dx.doi.org/10.3390/idr14010011
_version_ 1784657263612395520
author Xinias, Ioannis
Mavroudi, Antigoni
Theodorou, Georgios-Theofilos
Roilidis, Ioannis
author_facet Xinias, Ioannis
Mavroudi, Antigoni
Theodorou, Georgios-Theofilos
Roilidis, Ioannis
author_sort Xinias, Ioannis
collection PubMed
description We report our experience regarding a 56-year-old physician who developed severe symptoms mimicking a heart attack a few days after receiving the second dose of the new mRNA vaccine of Pfizer-BioNTech for COVID-19 protection. The patient is a healthy individual with no comorbidities and a normal clinical and laboratory profile. Five days after receiving the second dose on his left shoulder, he manifested sudden, severe pain on the whole left arm which lasted for about one hour, gradually intensifying and migrating to the chest and presenting as severe angina or heart attack. All work-up, however, was negative, with no evidence of ischemic heart attack or myocarditis. Severe acute symptoms lasted for about 20 h and completely resolved after 36 h. Although myocarditis as a potential side effect of the vaccine with associated heart pain has been identified, chest pain mimicking heart attack with otherwise normal workup has not been reported. Physicians must consider this likely rare and self-resolving symptom in order to increase awareness and prevent themselves and their patients from increased anxiety and unnecessary laboratory investigations.
format Online
Article
Text
id pubmed-8872543
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-88725432022-02-25 COVID-19 mRNA Vaccination Mimicking Heart Attack in a Healthy 56-Year-Old Physician Xinias, Ioannis Mavroudi, Antigoni Theodorou, Georgios-Theofilos Roilidis, Ioannis Infect Dis Rep Case Report We report our experience regarding a 56-year-old physician who developed severe symptoms mimicking a heart attack a few days after receiving the second dose of the new mRNA vaccine of Pfizer-BioNTech for COVID-19 protection. The patient is a healthy individual with no comorbidities and a normal clinical and laboratory profile. Five days after receiving the second dose on his left shoulder, he manifested sudden, severe pain on the whole left arm which lasted for about one hour, gradually intensifying and migrating to the chest and presenting as severe angina or heart attack. All work-up, however, was negative, with no evidence of ischemic heart attack or myocarditis. Severe acute symptoms lasted for about 20 h and completely resolved after 36 h. Although myocarditis as a potential side effect of the vaccine with associated heart pain has been identified, chest pain mimicking heart attack with otherwise normal workup has not been reported. Physicians must consider this likely rare and self-resolving symptom in order to increase awareness and prevent themselves and their patients from increased anxiety and unnecessary laboratory investigations. MDPI 2022-01-27 /pmc/articles/PMC8872543/ /pubmed/35200439 http://dx.doi.org/10.3390/idr14010011 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Xinias, Ioannis
Mavroudi, Antigoni
Theodorou, Georgios-Theofilos
Roilidis, Ioannis
COVID-19 mRNA Vaccination Mimicking Heart Attack in a Healthy 56-Year-Old Physician
title COVID-19 mRNA Vaccination Mimicking Heart Attack in a Healthy 56-Year-Old Physician
title_full COVID-19 mRNA Vaccination Mimicking Heart Attack in a Healthy 56-Year-Old Physician
title_fullStr COVID-19 mRNA Vaccination Mimicking Heart Attack in a Healthy 56-Year-Old Physician
title_full_unstemmed COVID-19 mRNA Vaccination Mimicking Heart Attack in a Healthy 56-Year-Old Physician
title_short COVID-19 mRNA Vaccination Mimicking Heart Attack in a Healthy 56-Year-Old Physician
title_sort covid-19 mrna vaccination mimicking heart attack in a healthy 56-year-old physician
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872543/
https://www.ncbi.nlm.nih.gov/pubmed/35200439
http://dx.doi.org/10.3390/idr14010011
work_keys_str_mv AT xiniasioannis covid19mrnavaccinationmimickingheartattackinahealthy56yearoldphysician
AT mavroudiantigoni covid19mrnavaccinationmimickingheartattackinahealthy56yearoldphysician
AT theodorougeorgiostheofilos covid19mrnavaccinationmimickingheartattackinahealthy56yearoldphysician
AT roilidisioannis covid19mrnavaccinationmimickingheartattackinahealthy56yearoldphysician