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Impact of Variants in the ATIC and ARID5B Genes on Therapeutic Failure with Imatinib in Patients with Chronic Myeloid Leukemia

Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm derived from the balanced reciprocal translocation of chromosomes 9 and 22 t (9q34 and 22q11), which leads to the formation of the Philadelphia chromosome and fusion of the BCR-ABL genes. The first-line treatment for CML is imatinib, a...

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Detalles Bibliográficos
Autores principales: Cereja Pantoja, Karla Beatriz Cardias, Azevedo, Tereza Cristina de Brito, de Carvalho, Darlen Cardoso, Monte, Natasha, Cohen Paes, Amanda de Nazaré, Barros, Maria Clara da Costa, Vinagre, Lui Wallacy Morikawa Souza, de Freitas, Ana Rosa Sales, Burbano, Rommel Mario Rodríguez, de Assumpção, Paulo Pimentel, dos Santos, Sidney Emanuel Batista, Fernandes, Marianne Rodrigues, dos Santos, Ney Pereira Carneiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872593/
https://www.ncbi.nlm.nih.gov/pubmed/35205374
http://dx.doi.org/10.3390/genes13020330